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Evaluate the efficacy and safety of LR08 as a dietary supplement compared to a placebo in enhancing intestinal health and immune function in healthy adults.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Probiotic group | Active Comparator | Intervention with probiotic LR08 (30 billion CFU/day, 3g) was administered daily for 8 weeks. |
|
| Placebo group | Placebo Comparator | Every day to give 3 g maltodextrin intervention for 8 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotic | Dietary Supplement | The trial period of this study lasts for 2 months(8weeks), during which each participant will have 3 visits (at month 0, month 1, andmonth 2). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Immune Function | Evaluation of immune function markers, specifically immunoglobulin A (IgA) concentration, to assess the effects of LR08 supplementation compared to placebo. | Week 0 and Week 8 |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xu fei | Zhengzhou | Henan | 210095 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41650801 | Derived | Han M, Xu F, Dong Y, Zhu J, Fang S, Zhao L. Safety and immune-regulating effects of Limosilactobacillus reuteri LR08: Preclinical and clinical evidence from a randomized controlled trial. Clin Nutr. 2026 Mar;58:106582. doi: 10.1016/j.clnu.2026.106582. Epub 2026 Jan 20. |
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| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| Placebo | Dietary Supplement | The trial period of this study lasts for 2 months(8weeks), during which each participant will have 3 visits (at month 0, month 1, andmonth 2). |
|
| D019602 |
| Food and Beverages |