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Evaluate the effectiveness and safety of Limosilactobacillus fermentum LF61 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Probiotic group | Active Comparator | Intervention with Limosilactobacillus fermentum LF61 (30 billion CFU/ day, 3g) was administered daily for 8 weeks. |
|
| Placebo group | Placebo Comparator | Every day to give 3 g maltodextrin intervention for 8 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotic | Dietary Supplement | Dietary supplement: Probiotics. The trial period of this study lasts for 2 months (8 weeks), during which each participant will have 3 visits (at month 0, month 1, and month 2). |
| Measure | Description | Time Frame |
|---|---|---|
| Change of concentration of antimicrobial peptide LL-37 | Detected by Enzyme-Linked Immunosorbent Assay (ELISA). | Week 0 and Week 8 |
| Change in calcarein concentration | Detected by Enzyme-Linked Immunosorbent Assay (ELISA). | Week 0 and Week 8 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xu Fei, Doctor | Contact | 13671979116 | +86 | xu.fei@haut.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xu fei | Zhengzhou | Henan | 210095 | China |
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| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| Placebo | Dietary Supplement | Dietary supplement: Placebo. The trial period of this study lasts for 2 months (8 weeks), during which each participant will have 3 visits (at month 0, month 1, and month 2). |
|
| D019602 |
| Food and Beverages |