The Effect of Environmental Factors on Gastric Cancer Based on Macrogenome

Study on the Development and Prognosis of Gastric Cancer Based on Environmental Factors and Macrogenome

The objectives of this study were to clarify how environmental factors such as air pollution affect the occurrence and development of gastric cancer; to identify patient-specific macrogenomic markers of gastric cancer; and to investigate the mechanism of gastric cancer development based on environmental factors and macrogenomic data.

Inclusion Criteria:

• age ≥ 18 years;
• patients with preoperative diagnosis of gastric cancer confirmed by pathologic biopsy;
• no chemotherapy, radiotherapy, targeted and immunotherapy, etc. before enrollment;
• willing to participate in the study and sign the informed consent form;
• complete clinical data.

Exclusion Criteria:

• concurrent primary malignant tumor other than gastric cancer;
• patients with systemic diseases, such as severe cardiopulmonary;
• insufficiency, that affect the choice of treatment plan;
• not suitable for enrollment as assessed by the investigator;
• incomplete clinical data.