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For stroke patients, a challenging, unfamiliar, and more difficult task may increase the likelihood of brain activation to stimulate recovery. Pedal walking and walking with eyes-covered are both difficult and challenging tasks for stroke patients. The investigators intend to study the biomechanics and neural mechanisms of challenging pedal walking and walking with eyes covered.
Stroke participants will wear electroencephalogram electrode caps and perform three tasks: walking on a flat surface for 60 seconds, walking on pedal for 60 seconds, and walking with eyes covered for 60 seconds.
Stroke participants will wear a 32-lead electroencephalogram electrode cap (Zhentai Technology Company, Xi 'an, China), first walk on a flat ground for 60 seconds, rest for 2 minutes, then walk on the pedal for 60 seconds, rest again for 2 minutes, and walk for 60 seconds with eyes-covered.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| stroke participants | Stroke participants with residual abnormal gait. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pedal walking | Other | Pedal walking is a challenging walking task that can be used as a form of physical therapy for stroke participants. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Weight Phase Lag Index | The Weighted Phase Lag Index (WPLI) is a measure used to quantify phase synchronization in electrophysiological data.Continuously measure the connectivity of the coupling of neural oscillatory activity in the brain, while being statistically more powerful in detecting changes in signal phase synchronization.The WPLI ranges from 0 to 1, with 0 indicating no phase synchronization and 1 indicating complete phase synchronization. | The study was an observational cross-sectional study with data collected at the same time as the trial was being conducted, so the duration was 60 seconds |
| Relative power | The electroencephalogram signal in the time domain is converted into the relevant information in the frequency domain, the frequency bands are divided, and the relative power results of each channel in each frequency band are derived. Among them, delta:1-4Hz, theta:4-8Hz, alpha:8-15Hz, beta:15-30Hz, gamma:30-45Hz. | The study was an observational cross-sectional study with data collected at the same time as the trial was being conducted, so the duration was 60 seconds |
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Inclusion Criteria:
Exclusion Criteria:
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Stroke patients, including outpatients and inpatients.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jing Zhao, master | Contact | +8618817892579 | 18817892579@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Xia Li Zhang, doctor | Geriatric Hospital of Nanjing Medical University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Geriatric Hospital of Nanjing Medical University, 269 Qingmen Street | Recruiting | Nanjing | Jiangsu | 210000 | China | |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16415682 | Background | Krakauer JW. Motor learning: its relevance to stroke recovery and neurorehabilitation. Curr Opin Neurol. 2006 Feb;19(1):84-90. doi: 10.1097/01.wco.0000200544.29915.cc. | |
| 34182403 | Background | Fettrow T, Hupfeld K, Tays G, Clark DJ, Reuter-Lorenz PA, Seidler RD. Brain activity during walking in older adults: Implications for compensatory versus dysfunctional accounts. Neurobiol Aging. 2021 Sep;105:349-364. doi: 10.1016/j.neurobiolaging.2021.05.015. Epub 2021 May 31. |
| Label | URL |
|---|---|
| This paper suggests that the rehabilitation of stroke patients may require more challenging tasks | View source |
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all IPD that underlie results in a publication.
Six months after publication.
Request from the corresponding author by email.
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| visual occlusion | Other | Walking with eyes-covered is a challenging walking task that can be used as a form of physical therapy for stroke participants. |
|
| Geriatric Hospital of Nanjing Medical University |
| Recruiting |
| Nanjing |
| Jiangsu |
| 210000 |
| China |
|
| 37027387 | Background | Kulkarni A, Cui C, Rietdyk S, Ambike S. Humans prioritize walking efficiency or walking stability based on environmental risk. PLoS One. 2023 Apr 7;18(4):e0284278. doi: 10.1371/journal.pone.0284278. eCollection 2023. |
| This paper suggests that the performance of complex walking tasks may involve top-down cortical control in the brain centers | View source |
| This paper shows that the central nervous system will actively respond to environmental changes and adjust to obtain stable motor output | View source |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |