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The study aims to use novel mobile imaging techniques with high-density electroencephalography (EEG) to quantify cortical processes synchronized to the biomechanics of walking. Here, the study has two aims - the primary aim is to quantify the cortical processes that contribute to gait dysfunction early post-stroke, and the second aim is to determine how cortical processes are mediated by mechanical assistance during early gait training post-stroke.
Participants will wear an electroencephalography (EEG) cap to measure brain activity and other non-invasive physiological sensors. Participants will be asked to perform different tasks, such as walking at different speeds and walking with different levels of body weight support.
This study will recruit 15 subacute post-stroke individuals and 15 age-matched neurotypical individuals between the age of 18-80 years old.
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| Measure | Description | Time Frame |
|---|---|---|
| Brain activity during walking measured by EEG | Changes in brain activity during walking with different levels of weight support | through study study completion, an average of 2 years |
| Brain activity during walking measured by EEG | Differences in brain activity during walking between people post-stroke and neurotypical individuals | through study study completion, an average of 2 years |
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Inclusion Criteria for post-stroke patients:
Exclusion Criteria for age-matched adults:
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Post-stroke participants (age 18-80), age-matched adults (age 18-80)
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| Name | Affiliation | Role |
|---|---|---|
| Chang Liu, PhD | University of Florida | Principal Investigator |
| Daniel Ferris, PhD | University of Florida | Principal Investigator |
| Dorian Rose, PT, PhD | University of Florida | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Florida | Gainesville | Florida | 32610 | United States |
Share deidentified data on an online repository
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| ID | Term |
|---|---|
| D020521 | Stroke |
| D051346 | Mobility Limitation |
| D006379 | Helping Behavior |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012919 | Social Behavior |
| D001519 | Behavior |