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The goal of the study is to compare different types of high intensity circuit exercises over an 8-class training series in people with Parkinson disease. The main question it aims to answer is:
-Does including arm and hand exercises with leg exercises improve reaction time, balance, functional measures, gait speed and quality of life? This group will be compared to a group that only does leg exercises. Participants will be asked to participate in 8 high intensity circuit exercise classes.
People with Parkinson disease will be recruited from the community and randomized into 2 equal groups: high intensity interval circuit training with lower extremity (LE) and lower and upper extremity (LEUE) training. The study will be composed of a baseline assessment, 8 group class sessions, and a post-intervention assessment. The baseline assessment will include demographics, disease and fall history and outcome measure collection. Group class sessions will include concurrent group warmup, followed by an 8-station circuit performed with high intensity intervals, and a cool-down. The circuit will include 4 stations performed by both the LE and LEUE groups and 4 stations specific to each intervention group, including 4 additional LE exercise stations for the LE group and 4 UE specific stations for the LEUE group. The stations that differ will not be adjacent to one another nor specifically indicated as different. The stations that differ will mirror similar aspects of function (ie, strength, reaction time, etc.) for the UE and LE stations. Participants will be told exercise stations may vary within-session and week to week but will not be informed that only one group has UE exercise interventions. After conclusion of the class series, post-intervention balance and stepping outcomes will be reassessed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lower extremity and upper extremity exercise | Experimental | Exercises in the circuit (8 total) will focus on the lower extremity (4) and upper extremity (4) |
|
| Lower extremity exercise | Active Comparator | Exercises in the circuit (8 total) will focus on the lower extremity (4) alone. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High intensity circuit exercise class - Lower and upper extremity | Other | Exercises performed at high intensity effort in the circuit (8 total) will focus on both the lower extremity (4) and upper extremity (4) |
| Measure | Description | Time Frame |
|---|---|---|
| Trail making Test Parts A and B (timed, higher scores mean worse outcome) | Cognitive and fine motor skills | 8-10 weeks |
| Activity-specific Balance Confidence Scale (0-100%, higher scores mean better outcome) | Balance confidence self-report | 8-10 weeks |
| Timed Up and Go | Balance and function | 8-10 weeks |
| 10 meter Walk Test | Gait Speed | 8-10 weeks |
| 6 minute walk test | endurance | 8-10 weeks |
| 9-hole peg test (timed, higher scores mean worse outcome) | fine motor | 8-10 weeks |
| Parkinson's Disease Questionnaire - Short Form (8) (Score 0-32, higher scores mean worse outcome) | Quality of Life | 8-10 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Tiffany B Salido, DPT, PhD | Pacific Northwest University of Health Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pacific Northwest University of Health Sciences | Yakima | Washington | 98901 | United States |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Single center, two arm, pre-test post-test parallel design with up to 4 cohorts of class participants.
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Participants will be told exercise stations may vary within-session and week to week but will not be informed that only one group has UE exercise interventions.
Assessors are blinded to group allocation.
| High intensity circuit exercise class - Lower extremity alone | Other | All exercises performed at high intensity effort in the circuit (8 total) will focus on the lower extremity alone |
|
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D001519 | Behavior |