Strength-Endurance Circuit Training in Parkinson's Disease

Strength-Endurance Circuit Training in Parkinson's Disease: Effects on Disease Severity, Physical Performance, Blood Biomarkers and Quality of Life.

The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.

- Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training?

Participants will:

• undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement,
• visit the clinic twice a week for 1-hour training sessions.
• selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period

Inclusion Criteria:

• age ≥18 years
• diagnosis of idiopathic Parkinson´s disease
• Hoehn-Yahr Scale ≤ 2,5
• stable dopaminergic medication

Exclusion Criteria:

• age ≥75 years
• Hoehn-Yahr Scale ≥ 2,5
• deep brain stimulation
• presence of freezing
• Camptocormia
• inability to walk without support
• inability to perform study procedures
• limiting co-morbidities
• attendance at training sessions below 70%