Brain Mechanism and Outcome of Surgical Intervention of Conductive Hearing Loss.

The Brain Network Mechanism and Outcome After Surgical Intervention of Conductive Hearing Loss Accompanied by Tinnitus.

This study explores the brain region activation and remodeling of poor connections of brain regions in the postoperative outcomes of conductive hearing loss patients with tinnitus by comparing pre - and post-operative audiological assessment, tinnitus assessment and EEG data.

This study explores the brain region activation and remodeling of poor connections of brain regions in the postoperative outcomes of conductive hearing loss patients with tinnitus by comparing pre - and post-operative audiological assessment, tinnitus assessment and EEG data. Including audiological assessment (pure tone audiometry, speech test), tinnitus assessment (tinnitus matching, tinnitus handicap inventory, tinnitus function index, visual analogue scale)and non-invasive brain imaging assessment (EEG, fNIRS).

Inclusion Criteria:

• aged between 18 and 60 years;
• diagnosed with conductive hearing loss with tinnitus;
• treated with surgery;
• able to cooperate with all Chinese version evaluation;
• right-handed.

Exclusion Criteria:

• Pure tone audiometry indicates that the average pure tone hearing threshold (500Hz, 1kHz, 2kHz, 4kHz) is > 91dB HL;
• acoustic neuroma, nasopharyngeal carcinoma;
• hearing loss caused by noise or drugs.