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| ID | Type | Description | Link |
|---|---|---|---|
| CFSNCC2013 | Other Grant/Funding Number | Universidade de BrasÃlia |
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This study aimed at trying transcranial magnetic stimulation and transcranial direct current stimulation as potential treatments to decrease tinnitus in patients with significant hearing loss.
Tinnitus is a very common condition and affects approximately 15% of the population, disrupting sleep, emotional balance and social life of the patients. Acoustic deprivation causes hearing loss and is responsible for a cascade of processes that result in the reorganization of the cortex through a synchronization of neuronal activity related to a cortical re-mapping. Consistent with the hypothesis that tinnitus is caused by abnormal activation of the auditory cortex, repetitive transcranial magnetic stimulation (rTMS) can temporarily reduce cortical hyperactivity through direct neuromodulation of the temporal cortex. Furthermore, studies have shown that transcranial direct current stimulation (tDCS) can also suppress tinnitus. Objective: To determine the effectiveness of rTMS and TDCS in the treatment of patients with chronic tinnitus and auditory loss. Methods: We performed an analytical experimental double-blind study using rTMS and tDCS in patients with chronic tinnitus and hearing loss.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Transcranial Magnetic Stimulation | Active Comparator | Patients receiving real transcranial magnetic stimulation |
|
| Sham TMS | Placebo Comparator | Patients receiving sham transcranial magnetic stimulation |
|
| Transcranial Direct Current Stimulation | Active Comparator | Patients receiving real transcranial direct current stimulation |
|
| Sham TDCS | Placebo Comparator | Patients receiving sham transcranial direct current stimulation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcranial Magnetic Stimulation | Procedure | TMS over the left temporoparietal cortex |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Tinnitus Handicap Inventory (THI) scores | THI was measured before intervention (baseline) and after 5 daily sessions (day 5) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Visual Analog Scale scores | Visual analog scale of tinnitus was recorded at baseline and after daily 5 TMS or TDCS sessions ( day 5) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Joaquim P Brasil-Neto, PhD | University of Brasilia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidade de BrasÃlia | BrasÃlia | Federal District | 70000 | Brazil |
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| ID | Term |
|---|---|
| D014012 | Tinnitus |
| D034381 | Hearing Loss |
| ID | Term |
|---|---|
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012678 | Sensation Disorders |
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| ID | Term |
|---|---|
| D050781 | Transcranial Magnetic Stimulation |
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D055909 | Magnetic Field Therapy |
| D013812 | Therapeutics |
| D004599 | Electric Stimulation Therapy |
| D003295 | Convulsive Therapy |
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| Transcranial Direct Current Stimulation | Procedure | TDCS over the left temporoparietal cortex |
|
| D009461 |
| Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D013000 |
| Psychiatric Somatic Therapies |
| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |