The purpose of the present study is to compare the effect of injectable platelet fibrin and Low Level LASER therapy on the rate of upper canine retraction, and on root resorption of the canine

the study involves two groups the first group received low level laser at the upper right canine, while the upper left canine act as a control. The second group received injectable platelet rich fibrin at the upper right canine, while the upper left canine act as a control. in each group we will compare rate of canine retraction between both sides, and amount of root resorption also we will compare both groups regarding rate of canine retraction and amount of root resorption

Inclusion Criteria:

1. Patients with age 18 years or older.
2. Presence of all permanent teeth except for the third molar.
3. Presence of malocclusion requiring maxillary first premolar extraction such as (class II division 1 or bimaxillary dentoalveolar protrusion).

Exclusion Criteria:

1. Patient with a history of previous orthodontic treatment.
2. Medical problems may interfere with orthodontic treatment.
3. Bad oral hygiene.