Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The prevalence of chronic diseases is increasing globally. In recent years, intermittent fasting has emerged as an effective dietary pattern against some of the most common chronic diseases in the elderly, alongside the Mediterranean diet.
The objective was to determine whether a 12-hour daily intermittent fasting regimen combined with a Mediterranean diet can improve analytical and anthropometric values in the elderly.
A total of 17 individuals of both sexes, over 60 years old, autonomous, and with preserved cognitive capacity participated. They were randomly divided into two groups: 8 people in the intervention group performed intermittent fasting along with a Mediterranean diet, and 9 in the control group adopted only a Mediterranean diet. The intervention lasted 3 months, with measurements taken at the beginning and end of the intervention.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Time Restricted Feeding (TRF) | Experimental | 8 participants who followed a 12/12 Time Restricted Feeding (12 consecutive hours of fasting, from 20:30 to approximately 8:30 the following day). |
|
| Mediterranean diet | Active Comparator | A control group consisting of 9 participants who followed a standard Mediterranean diet. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Time Restricted Feeding | Other | 8 participants who practiced a 12/12 TRF (12 hours of fasting, from approximately 20:30 to 8:30 the following day). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Biochemical values (mg/dL) | Basal glucose, High-Density Lipoprotein, Low-Density Lipoprotein, total cholesterol, triglycerides, serum transferrin, urea, uric acid, creatinine. | 12 weeks |
| Blood Pressure (mmHg) | Blood pressure (Systolic blood pressure, diastolic blood pressure) | 12 weeks |
| Anthropometric values (kg) | Weight | 12 weeks |
| Anthropometric values (cm) | Weight, waist circumference, hip circumference. | 12 weeks |
| Anthropometric values (kg/m^2) | Body mass index. | 12 weeks |
| Anthropometric index (numerical rating scale) | Atherogenic index of plasma, waist/hip ratio. | 12 weeks |
| Biochemical values (IU/L) | Alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase | 12 weeks |
| Biochemical values (mg/L) | C-Reactive Protein | 12 weeks |
| Biochemical values (µg/L) |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Zaragoza | Zaragoza | Spain |
Not provided
Not provided
Not provided
Not provided
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Mar 26, 2025 | |
| Reset | Apr 11, 2025 | |
| Release | Jan 13, 2026 | |
| Reset | Jan 29, 2026 | |
| Release | Apr 28, 2026 | |
| Reset | May 20, 2026 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Mar 26, 2025 | Apr 11, 2025 | |||
| Jan 13, 2026 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D006973 | Hypertension |
| D050171 | Dyslipidemias |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D038441 | Diet, Mediterranean |
| ID | Term |
|---|---|
| D000095500 | Diet, Plant-Based |
| D004035 | Diet Therapy |
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Mediterranean Diet | Other | A control group consisting of 9 participants who followed a standard Mediterranean diet. |
|
Serum ferritin |
| 12 weeks |
| Biochemical values (µg/dL) | Iron | 12 weeks |
| Biochemical values (g/dL) | Albumin | 12 weeks |
| Jan 29, 2026 |
| Apr 28, 2026 | May 20, 2026 |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D052439 | Lipid Metabolism Disorders |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D004032 |
| Diet |
| D009747 | Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |