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The research aims to understand oceans as crucial contributors to human health in coastal environments. Oceans produce marine spray aerosols that contain a mixture of microbiota and natural biological molecules (biogenics).
The primary outcome envisioned consists of 2 goals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group lives inland, but spends a lot of time at the coast during study period | Other | This group lives inland, but spends a lot of time at the coast during the study period. |
|
| reference group coast | Other | This group lives at the coast the whole year round |
|
| reference group inland | Other | This group lives inland all year round. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no intervention | Other | no intervention, people just indicate if they spend time inland or at the coast |
|
| Measure | Description | Time Frame |
|---|---|---|
| nose swabs: respiratory microbiome and biogenics profile | DNA from the nose swabs will be analysed using sequencing for analyzing the microbiome. Biogenics on the swabs will be analysed as well, to get an idea of what molecules and microbiota from the sea air are inhaled. This will happen with UPLC-QTOF-MS. | 4 times during the 8 week study period |
| VAMS blood samples: cytokines | Cytokines will be measured in blood samples to link the sea air exposure to the human health. A multiplex kit will be used to measure 20 cytokines. | 4 times during the 8 week study period |
| GPS | via sensorlogger app on their phone, to collect GPS data when outside. | during the 8 week study period, if more than 15 minutes spend outside |
| questionnaires | Filling in a questionnaire via qualtrics | at the start, in the middle and at the end of the 8 weeks. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hannelore Denys | University Ghent | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ghent University | Ghent | Oost-Vlaanderen | 9000 | Belgium |
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three groups: one group that lives at the coast all year round, one group that lives inland all year round and one group that live inland but spend a lot of time at the coast in the summer.
The participants will not get any treatment, they just live in different regions.
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