CompletedInterventionalNot ApplicableUpdated Jan 26, 2021
Glymphatic MRI Study | NCT06452459 | Trialant
Not yet recruitingObservationalUpdated Jun 11, 2024
Glymphatic MRI Study
Evaluation of Glymphatic Function With MRI
ClinicalTrials.gov ID
NCT06452459
Lead Sponsor
Oregon Health and Science UniversityOTHER
Overall Status
Not yet recruiting
Study Type
Observational
Enrollment
10Estimated
Last Update Posted
Jun 11, 2024Actual
Start Date
Jul 1, 2024Estimated
Primary Completion Date
Jul 1, 2027Estimated
Completion Date
Jul 1, 2028Estimated
Official Title
Evaluation of Glymphatic Function With MRI
Brief Summary
This study aims at identifying neuroimaging markers of glymphatic function in humans.
Sleep Deprivation
No interventinon
Ages Eligible for Study
Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
No data available
Eligibility Criteria
Inclusion Criteria:
Ability to undergo MRI without anesthesia
Calculated GFR greater or equal to 60 mL/min/1.73 m2
Exclusion Criteria:
Inability to obtain consent
Subject is incarcerated, pregnant, or lactating or suspects they may be pregnant
Known allergic or hypersensitivity reactions to gadolinium
Three or more drug allergies from separate drug classes
Recent or expected beed for imaging with iodinated contrast
Contraindications to MRI: claustrophobia, weight greater than maximum MRI scanner capacity, presence of metallic foreign body, or implanted devices not documented as MRI safe
History of neurosurgical procedure or cervical surgery
Current use of anticoagulation medications
Contraindication to lumbar puncture (creatinine or INR elevated above laboratory standard cutoffs)