Quantitation of Glymphatic Functioning in Sleep and Meditative States

Quantitation of Glymphatic Functioning in Sleep and Meditative States

This involves development and application of magnetic resonance imaging (MRI) methods for visualizing hemodynamic and metabolic relationships in healthy volunteers with advanced meditation experience.

This study is evaluating the glymphatic system during awake, sleep, and meditative states.

Inclusion Criteria:

• Ages 14-45
• "Adept meditator status"

Exclusion Criteria:

• Any non-MR compatible material implant, or contraindication to MR scanning
• Claustrophobia or inability to lie still for prolonged periods of time
• Participants with a recent (less than 2 months) infection, tattoo, or wound
• No consumption of stimulants or alcohol within 12 hours of the study visit
• clinical diagnosis of any major neurological or psychological condition
• Taking benzodiazepines, cholinestorase inhibitors, anti-psychotics, opioids, MAO inhibitors