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explore objective indicators of the efficacy of natural psychotherapy in the treatment of disorders such as obsessive-compulsive disorder
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Natural Psychotherapy intervention for obsessive-compulsive disorder | Experimental | Inpatient naturopathic treatment was performed once a day for 45 consecutive days |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Natural psychotherapy | Other | Draw ideas from traditional Chinese culture, learn from the practice of Morita therapy in Japan, and create local practice experience. At the same time, a variety of research methods such as cognitive assessment and brain imaging were used to establish the scientific, professional and objective evaluation indexes of the therapy. |
| Measure | Description | Time Frame |
|---|---|---|
| Obsessive-compulsive symptoms | Obsessive-compulsive symptoms were assessed according to the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), The total score ranges from 0 to 40, with higher scores indicating more severe symptoms. | Baseline, 12 weeks |
| Cognitive function | Cognitive inhibition was assessed using the emotional color-word Stroop task. The emotional Stroop task is a type of being Widely used cognitive inhibition assessment tools. The longer the reaction time, the worse the cognitive inhibition ability. | Baseline, 12 weeks |
| Mood and behavior | Mood changes judged using gait and face recognition | Baseline, 12 weeks |
| ERP components associated with cognitive function | To explore the ERP component analysis related to cognitive inhibition and Behavioral inhibition in obsessive-compulsive disorder (OCD) by event related potential (ERP) analysis | Baseline, 12 weeks |
| rest fMRI in Obsessive-compulsive patients | The changes of resting-state functional connectivity were analyzed in patients with OCD before and after intervention. Resting-state functional connectivity:FC(Functional connectivity). Resting-state functional brain imaging data were collected using a GE 3.0T magnetic resonance scanner (GE Discovery MR750) at the Brain Imaging Center, Institute of Psychology, Chinese Academy of Sciences. | Baseline, 12 weeks |
| Behavioral inhibition | behavioral inhibition was assessed using the emotional stop signal task (SST). The emotional SST task is a type of being Widely used behavioral inhibition assessment tools. Among them, the greater the SSRT, the worse the behavioral inhibition ability. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhang Y Xiang, M.D., Ph.D | Contact | +86-10-62710644 | zhangxy@psych.ac.cn |
| Name | Affiliation | Role |
|---|---|---|
| Xiang-Yang Zhang, M.D., Ph.D | Institute of Psychology, Chinese Academy of Science | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anhui Mental Health Center | Recruiting | Hefei | Anhui | 230022 | China |
Data with be available on request
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| ID | Term |
|---|---|
| D009771 | Obsessive-Compulsive Disorder |
| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| D001523 | Mental Disorders |
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| Baseline, 12 weeks |
| Institute of Psychology, Chinese Academy of Sciences | Recruiting | Beijing | China |
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