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explore objective indicators of the efficacy of natural psychotherapy in the treatment of disorders such as obsessive-compulsive disorder
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Natural Psychotherapy | Active Comparator | Intervention using natural psychotherapy for OCD patients for two to three hours once a week for eight weeks |
|
| waitlist control group | Other | The waiting group will not undergo any intervention adjustments within the next two months and will not receive any other psychological interventions. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Natural Psychotherapy | Behavioral | Natural psychotherapy is based on "Morita therapy" and is a psychotherapy that fully reflects the characteristics of Chinese culture, taking into account the Chinese cultural background and actual clinical characteristics. |
| Measure | Description | Time Frame |
|---|---|---|
| Obsessive-compulsive symptoms | Using the score of Yale-Brown Obsessive-Compulsive Scale as the primary outcome, a decrease in score of ≥35% was considered a 'response to treatment', also referred to as a 'full response', and a decrease in score of ≥25% was considered a 'partial response' | Baseline, week 4, week 8 |
| Measure | Description | Time Frame |
|---|---|---|
| Self-reported obsessive-compulsive symptoms | The reduction rate of the score of Obsessive-Compulsive Inventory-Revised (OCI-R), a self-rating scale of OCD symptoms severity, was employed as a secondary outcome | Baseline, week 4, week 8 |
| Cognitive inhibition |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Xiang Y Zhang, M.D, Ph.D | Institute of Psychology, Chinese Academy of Science | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anhui Mental Health Center | Hefei | Anhui | 230022 | China | ||
| Institute of Psychology, Chinese Academy of Sciences |
Data with be available on request
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| ID | Term |
|---|---|
| D009771 | Obsessive-Compulsive Disorder |
| ID | Term |
|---|---|
| D001008 | Anxiety Disorders |
| D001523 | Mental Disorders |
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The patient was assigned to either the intervention group or the control group, but the control group would also receive treatment after a two-month waiting period. Therefore, the patient was only informed whether they would be participating in the first or second intervention.
| waitlist control group | Behavioral | waitlist control group |
|
Cognitive inhibition was assessed using the emotional color-word Stroop task. The emotional Stroop task is a type of being Widely used cognitive inhibition assessment tools. The longer the reaction time, the worse the cognitive inhibition ability. |
| Baseline, week 8 |
| Behavioral inhibition | Behavioral inhibition was assessed using the emotional stop signal task (SST). The emotional SST task is a type of being Widely used behavioral inhibition assessment tools. Among them, the greater the SSRT, the worse the behavioral inhibition ability. | Baseline, week 8 |
| ERP components associated with cognitive function | To explore the ERP component analysis related to cognitive inhibition and Behavioral inhibition in obsessive-compulsive disorder (OCD) by event related potential (ERP) analysis | Baseline, week 8 |
| rest fMRI in Obsessive-compulsive patients | The changes of resting-state functional connectivity were analyzed in patients with OCD before and after intervention. Resting-state functional connectivity:FC(Functional connectivity). Resting-state functional brain imaging data were collected using a GE 3.0T magnetic resonance scanner (GE Discovery MR750) at the Brain Imaging Center, Institute of Psychology, Chinese Academy of Sciences. | Baseline, week 8 |
| Beijing |
| China |
| 100096 |
| China |