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TrEnd trial is aimed to collect data from consecutive patients undergoing segmental sigmoid colon/rectal resection for deep endometriosis. The main purpose of this project is to gather a large series of cases treated using standardized surgical procedures, allowing a precise evaluation of complications and long-term outcomes.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Colorectal bowel resection | Procedure | The TrEnd is a single-institutional retrospective/prospective study, conducted in a high-volume referral centre for the endometriosis diagnosis and management, with the aim of systematically collecting data from consecutive patients undergoing segmental sigmoid colon/rectal resection for deep endometriosis. |
| Measure | Description | Time Frame |
|---|---|---|
| To document the surgical strategies adopted for treating patients with deep endometriosis undergoing to sigmoid colon/rectal resection | Percentage | 10 years |
| To assess the rate of complications | Rate/percentage | 10 years |
| To assess the rate of conversion to open surgery | Rate/percentage | 10 years |
| To assess the rate of endometriosis-free bowel resection margins | Rate/percentage | 10 years |
| To assess the rate of recurrence | Rate/percentage | 10 years |
| Measure | Description | Time Frame |
|---|---|---|
| To assess the intraoperative blood loss | Median with IQR | 10 years |
| To assess the operating time | Median time with IQR | 10 years |
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Inclusion Criteria:
Exclusion Criteria:
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Women undergoing segmental sigmoid colon/rectal resection for deep endometriotic nodules infiltrating the tunica muscularis of the sigmoid colon/rectum preoperatively identified with imaging and surgically treated with segmental resection
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mario Malzoni, MD | Contact | 0825796111 | +39 | malzonimario@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Mario Malzoni, MD | malzonimario@gmail.com | Principal Investigator |
| Francesca Falcone, MD | francescafalcone@malzoni.org | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Casa Di Cura Malzoni Villa Platani Spa | Recruiting | Avellino | Campania | 83100 | Italy |
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| To assess the gastrointestinal function recovery | Median days with IQR | 10 years |
| To assess the duration of hospital stay | Median days with IQR | 10 years |
| To assess the reproductive outcomes | Rate/percentage of pregnancies, normal full term deliveries, spontaneous and voluntary abortions | 10 years |