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This is a 2 x 2-factor crossover design study to investigate the effects of time of day and nuts on post-meal cognitive performance.
In this trial, eligible participants will receive isocaloric meals with or without nuts at lunchtime and dinner time. Cognitive performance will be performed before and 90 min after the meals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lunch nut-free meal | Placebo Comparator | Participants will receive an isocaloric meal without nuts at lunchtime. |
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| Lunch nut meal | Experimental | Participants will receive an isocaloric meal with nuts at lunchtime. |
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| Dinner nut-free meal | Placebo Comparator | Participants will receive an isocaloric meal without nuts at dinner. |
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| Dinner nut meal | Experimental | Participants will receive an isocaloric meal with nuts at dinner. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nuts | Other | Isocaloric meal with nuts |
| |
| Measure | Description | Time Frame |
|---|---|---|
| N-back task - accuracy | Difference in the total accuracy | before meal x 90 min post-meal |
| N-back task - matched responses | Difference in the % matched responses | before meal x 90 min post-meal |
| N-back task - false alarm | Difference in the % false alarm | before meal x 90 min post-meal |
| N-back task - reaction time | Difference in the reaction time for correct matched responses | before meal x 90 min post-meal |
| Stroop test - congruent | Difference in the reaction time for congruent | before meal x 90 min post-meal |
| Stroop test - incongruent | Difference in the reaction time for incongruent | before meal x 90 min post-meal |
| Stroop test - interference | Difference in stroop interference (incongruent - congruent response time) | before meal x 90 min post-meal |
| Measure | Description | Time Frame |
|---|---|---|
| Multitasking - pure blocks | Difference in the reaction time for pure blocks | before meal x 90 min post-meal |
| Multitasking - mixed blocks | Difference in the reaction time for mixed blocks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Barbara R Cardoso, PhD | Department of Nutrition, Dietetics and Food - Monash University | Principal Investigator |
| Maxine Bonham, PhD | Department of Nutrition, Dietetics and Food - Monash University | Principal Investigator |
| Helen Macpherson, PhD | Deakin University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Nutrition, Dietetics and Food - Monash University | Notting Hill | Victoria | 3168 | Australia |
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| ID | Term |
|---|---|
| D009754 | Nuts |
| ID | Term |
|---|---|
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
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2 x 2-factor crossover design study
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| Nut-free meal |
| Other |
Isocaloric meal without nuts |
|
| before meal x 90 min post-meal |
| Multitasking - mixing cost | Difference in mixing cost (mixed - pure reaction time) | before meal x 90 min post-meal |
| Satiety - hunger | Difference in postprandial hunger | Hunger will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). |
| Satiety - fullness | Difference in postprandial fullness | Fullness will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). |
| Satiety - satisfaction | Difference in postprandial satisfaction | Satisfaction will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). |
| Satiety - eating capacity | Difference in postprandial eating capacity, | Eating capacity will be assessed with a visual analog scale before the meal and 4 times after the meal (15, 30, 60 and 90 mins). |
| Satiety index | Difference in postprandial satiety index, calculated using the mean of the four satiety questions, where "hunger" and "eating capacity" will be scored in an inverse way than "fullness" and "satisfaction". | Satiety index will be assessed before the meal and 4 times after the meal (15, 30, 60 and 90 mins). |