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| Name | Class |
|---|---|
| Medical University of Vienna | OTHER |
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The aim of the present study is to investigate the effects of different meal interventions on cognition (i.e., learning and decision making) and brain activity in healthy participants.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standardized meal with macronutrient composition 1 | Experimental | Participants receive a standardized meal with one type of macronutrient composition in one experimental session and the other type in a different experimental session a few days apart (within-subjects crossover design; i.e. order counterbalanced) |
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| Standardized meal with macronutrient composition 2 | Experimental | Participants receive a standardized meal with one type of macronutrient composition in one experimental session and the other type in a different experimental session a few days apart (within-subjects crossover design; i.e. order counterbalanced) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dietary intervention: Standardized breakfast with varying amounts of macronutrients (in particular carbohydrate/protein ratios) | Other | Participants receive a standardized meal with one type of macronutrient composition in one experimental session and the other type in a different experimental session a few days apart (within-subjects crossover design; i.e. order counterbalanced) |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in cognition/behavior I | Changes in learning behavior assessed via computer-based learning task ("predictive inference task") which tracks choices and response times (allows for calculation of learning-related scores: change in prediction choice following feedback) | 3-4.5 hours (post-meal) |
| Changes in cognition/behavior II | Changes in decision-making behavior assessed via computer-based decision task ("gamble task") which tracks choices (calculation of gamble acceptance frequencies) and response times. | 3-4.5 hours (post-meal) |
| Changes in brain activity | Changes in brain activity measured via functional magnetic resonance imaging; | 3-4.5 hours (post-meal) |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in metabolic parameters I | Changes in the concentrations of amino acids (assessed via blood samples and chemical analysis) | from baseline (prior meal) to approx. 4.5 hours after meal at several time points |
| Changes in metabolic parameters II |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stefan Schulreich, Prof. Dr. | Contact | +4314277 | 54960 | stefan.schulreich@univie.ac.at |
| Name | Affiliation | Role |
|---|---|---|
| Stefan Schulreich, Prof. Dr. | University of Vienna | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Vienna | Recruiting | Vienna | 1090 | Austria |
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Changes in the concentrations of glucose (assessed via blood samples and chemical analysis)
| from baseline (prior meal) to approx. 4.5 hours after meal at several time points |
| Changes in metabolic parameters III | Changes in the concentrations of insulin (assessed via blood samples and chemical analysis) | from baseline (prior meal) to approx. 4.5 hours after meal at several time points |
| Changes in metabolic parameters IV | Changes in the concentration of cortisol (assessed via saliva samples and chemical analysis) | from baseline (prior meal) to approx. 4.5 hours after meal at several time points |
| Changes in subjective affective state | Changes in reported affect ("Multidimensionaler Befindlichkeitsfragebogen" - multidimensional mood scale; Steyer et al., 1997) | from baseline (prior meal) to approx. 4.5 hours after meal at several time points |
| Changes in experienced hunger | Changes in subjective reported hunger (assessed via single-item Likert-Scale) | rom baseline (prior meal) to approx. 4.5 hours after meal at several time points |