The objective of the study is to determine the presence of germinal elements of echinococcosis in the liver parenchyma next to and in the thickness of the fibrous capsule of hydatid cysts.

Inclusion Criteria:

• Presence of primary or recurrent liver echinococcosis disease requiring surgical treatment
• Cyst diametr >5 cm;
• Performing one of the surgical treatment of liver echinococcosis with intraoperative sampling of part of the fibrous capsule with or without adjacent liver tissue for research;
• Signed informed consent of patients for inclusion in the study;

Exclusion Criteria:

• Liver echinococcosis with cysts less than 5 cm in diametr;
• Presence of severe concomitant disorders

Patients with primary or recurrent liver echinococcosis