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The objective of the study is to improving the results of surgical treatment of liver echinococcosis complicated by biliary fistula by optimizing diagnostic approaches to early verification of this complication and improving the tactical and technical aspects of its elimination.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| operation for liver echinococcosis complicated by a biliary fistula | Other |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Conservative surgical treatment of liver echinococcosis, verification of occult biliary fistulas and their elimination by weaving and using medical cyanoacrylate glue | Procedure | In conservative surgical operations for liver echinococcosis, the biliary fistula is identified, onto which a U-shaped suture is applied, after which medical cyanoacrylate glue is applied between the suture stitches to the fibrous capsule in the fistula area and the suture threads are tied. |
| Measure | Description | Time Frame |
|---|---|---|
| Measuring the incidence of bile leakage after conservative surgical interventions for liver echinococcosis | assessing the effectiveness of the method for eliminating biliary fistulas in the fibrous capsule during organ-preserving surgeries for liver echinococcosis, characterized by creating a two-level strengthening of the fistula area by applying U-shaped sutures and a cyanoacrylate adhesive composition | 3 months |
| Measuring the time of closure of biliary fistulas in the postoperative period | In the group of patients with the development of biliary fistulas after surgery, the time of their closure in days will be studied | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Measuring the costs of treating patients with liver echinococcosis | Economic costs will be assessed for patients with liver echinococcosis who undergo conservative surgical interventions, taking into account the absence or development of bile leakage in the postoperative period | 3 months |
| Measurement of the quality of life of patients after conservative surgical interventions for liver echinococcosis. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov | Recruiting | Tashkent | 100000 | Uzbekistan |
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The quality of life will be analyzed using the SF-36 (The 36-Item Short Form Survey) questionnaire in patients after conservative surgical interventions, taking into account the absence or development of bile leakage in the postoperative period. It stems from a study called the Medical Outcomes Study for the objective measure of the quality of life. Scores for the various domains are transformed and combined using a scoring key to obtain a total score indicating a range from low to high quality of life (from 0 to 100 points). Scores for two components, the physical component and the mental component, can also be calculated. |
| 3 months |
| ID | Term |
|---|---|
| D004444 | Echinococcosis, Hepatic |
| D001658 | Biliary Fistula |
| ID | Term |
|---|---|
| D004443 | Echinococcosis |
| D002590 | Cestode Infections |
| D006373 | Helminthiasis |
| D010272 | Parasitic Diseases |
| D007239 | Infections |
| D008109 | Liver Diseases, Parasitic |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D016154 | Digestive System Fistula |
| D005402 | Fistula |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
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