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The goal of this study is to compare motor learning rates on two different tasks, when combined with non-invasive brain stimulation.
We will apply transcranial random noise stimulation or sham stimulation. During tRNS, participants will complete a grasping task or a reaching task. Each participant will complete both tasks, with a wait period between each task. Task order will be randomized, such that half the group will begin with each task. We will compare task scored before vs. after tRNS, for each task. This will be a measure of motor learning.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Grasp Task | Experimental | Participants will practice a fine motor grasping task for 20 min during tRNS or sham stimulation. |
|
| Reach Task | Experimental | Participants will practice a reaching task for 20 min during tRNS or sham stimulation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| transcranial random noise stimulation | Device | This intervention will give children tRNS during reaching or grasping repetitive movements. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in Grasp score | Participants will be asked to perform a grasping task, scored by number of pegs placed in a board. | Immediately before vs. Immediately after brain stimulation |
| Change in Reach score | Participants will be asked to perform a reaching task to stack cups, scored by time taken to stack all cups. | Immediately before vs. Immediately after brain stimulation |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Graded Redefined Assessment of Strength, Prehension assessment (GRASSP) | Participants will be asked to perform the GRASSP, scored by tallying points according to the test parametrics. | Immediately before vs. Immediately after brain stimulation |
| Change in score on second reaching task |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kathleen Friel, PhD | Contact | 19143683116 | kaf3001@med.cornell.edu | |
| Shivakeshavan Ratnadurai-Giriharan, PhD | Contact | 191436383160 | shr3006@med.cornell.edu |
| Name | Affiliation | Role |
|---|---|---|
| Kathleen Friel, PhD | Burke Neurological Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Burke Neurological Institute | White Plains | New York | 10605 | United States |
We will upload de-identified data onto our website and the NIH data sharing website (DASH).
Data will be uploaded within 2 months of study completion and will be available in perpetuity.
Potential users will need to join DASH to access our data. Anyone who completes the DASH registration will be able to access our data.
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| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
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| Sham stimulation | Device | This intervention will give children sham stimulation during reaching or grasping repetitive movements. |
|
Participants will be asked to perform a reaching task to stack cups in a different pattern from Primary Outcome #2, scored by time taken to stack all cups. |
| Immediately before vs. Immediately after brain stimulation |
| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |