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| Name | Class |
|---|---|
| Groupe de Pathologies Infectieuses Pédiatriques (GPIP) | OTHER |
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This study was set up because of an unusual increase in the number of cases of mycoplasma infections in France between June and November 2023.
Clinical data from children with mycoplasma infections will be collected to characterise this infection and facilitate hospital management.
In this study, the number of cases will be collected. In addition, we will determine the clinical, biological and microbiological characteristics of these cases.
These following data will be collected: signs or symptoms associated with this infection, clinical complications, biological and microbiological tests done during hospitalisation, treatment used during hospitalization, results of thoracic x-ray and lung ultrasound.
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| Measure | Description | Time Frame |
|---|---|---|
| Number of patients hospitalized for mycoplasma infections | Proportion of hospitalized children due to mycoplasma infections | 1 year |
| medical characterisation of mycoplasma infections | Assessment of clinical, biological and microbiological characteristics of mycoplasma infections cases. | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Identify risk factors of serious infection | Describe what is responsible of serious infection. | 1 year |
| Identify predictive signs of serious infection | what are the warning signs of a serious infection? |
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Inclusion Criteria:
Exclusion Criteria:
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hospitalised children under 18 age, with Mycoplasma infection
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| Name | Affiliation | Role |
|---|---|---|
| Corinne Levy | Association Clinique Thérapeutique Infantile du val de Marne | Study Director |
| Anais Chosidow | Hôpital Intercommunal de Villeneuve-Saint-Georges | Principal Investigator |
| Emilie Pauquet | Hôpital des Enfants, CHU de Bordeaux | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ACTIV | Créteil | 94600 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41274297 | Result | Chosidow A, Maakaroun-Vermesse Z, Ok V, Delecroix C, Le Roux P, Dommergues MA, de Larminat J, Jeziorski E, Ronjat P, Jaume L, Welfringer-Morin A, Bebear C, Gits-Muselli M, Viriot D, Roux CJ, Bechet S, Romain AS, Lorrot M, Cohen R, Levy C, Cohen JF; ORIGAMI Study Group. Post-COVID-19 resurgence of Mycoplasma pneumoniae infections in French children (ORIGAMI): a retrospective and prospective multicentre cohort study. Lancet Infect Dis. 2026 Apr;26(4):374-383. doi: 10.1016/S1473-3099(25)00598-5. Epub 2025 Nov 19. |
| Label | URL |
|---|---|
| Post-COVID-19 resurgence of Mycoplasma pneumoniae infections in French children (ORIGAMI): a retrospective and prospective multicentre cohort study | View source |
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| ID | Term |
|---|---|
| D009175 | Mycoplasma Infections |
| ID | Term |
|---|---|
| D009180 | Mycoplasmatales Infections |
| D016905 | Gram-Negative Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
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nasopharyngeal, oropharyngeal, lung, pleural puncture, pleural fluid, skin swab, cerebrospinal fluid, biopsy, etc... taken during routine care may be stored at hospital and analysed later. These data could be explored during end-of-study analysis.
| 1 year |
| Type of complications | Describe any complications due to infection | 1 year |
| Patients outcome | Proportion of patients recovered | 1 year |
| healthcare used for infected children | Describe healthcare provided during hospitalisation of infected children in order to manage this type of infection | 1 year |
| treatment used during hospitalisation | type of treatment used during hospitalisation to manage the infection | 1 year |
| clinical description of infected children | clinical description of all cases of mycoplasma infections reported during the study | 1 year |
| Type of mycoplasma involved in infected children | characterisation of mycoplasma involved in infection (strain, molecular epidemiology and antibiotic resistance) | 1 year |
| Assessment of Complementary Diagnostic Test Performance in Lung Disorders | To evaluate the performance of complementary diagnostic tests in children with lung disorders, including sensitivity, specificity, and agreement with standard diagnostic methods. | 1 year |
| Correlation between diagnostic test results in Infected Children | To evaluate the relationship between the results of various diagnostic tests in children with infection, aiming to identify patterns or predictors of disease severity. | 1 year |
| D007239 | Infections |