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The purpose of this study is to investigate the effect of casein protein consumption both prior to sleep as well first thing in the morning on metabolism (increase satiety and appetite, lower resting metabolic rate, and lower blood sugar levels), when compared to nighttime protein or placebo consumption alone. Protein itself is a macronutrient that not only helps the body repair itself, and play a critical role in growth, it also aids in increasing satiety and decreasing appetite. Casein protein specifically is slow digesting dairy protein which may impact the body's metabolism for a longer period than other dairy proteins such as whey. The literature demonstrates nighttime protein ingestion prior to sleep increases metabolic rate and satiety the next morning. However, there appears to be no data on the metabolic effects of protein ingested both at night and in the morning.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PRO pm, PRO am | Experimental | Participants arrive to the lab, complete 30 mins resting metabolic rate assessment. Then they are provided with a shake to drink 30 mins before bed. They return to the lab the following morning for 30 min RMR, drink another shake and do 30 mins RMR before leaving the lab. |
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| PRO pm, PLAC am | Experimental | Participants arrive to the lab, complete 30 mins resting metabolic rate assessment. Then they are provided with a shake to drink 30 mins before bed. They return to the lab the following morning for 30 min RMR, drink another shake and do 30 mins RMR before leaving the lab. |
|
| PLAC pm, PRO am | Experimental | Participants arrive to the lab, complete 30 mins resting metabolic rate assessment. Then they are provided with a shake to drink 30 mins before bed. They return to the lab the following morning for 30 min RMR, drink another shake and do 30 mins RMR before leaving the lab. |
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| PLAC pm, PLAC pm | Placebo Comparator | Participants arrive to the lab, complete 30 mins resting metabolic rate assessment. Then they are provided with a shake to drink 30 mins before bed. They return to the lab the following morning for 30 min RMR, drink another shake and do 30 mins RMR before leaving the lab. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| protein or placebo | Dietary Supplement | casein protein (30g) or placebo (maltodextrin, 30g) |
|
| Measure | Description | Time Frame |
|---|---|---|
| resting metabolic rate | indirect calorimetry to measure oxygen consumption (V02) and respiratory quotient (RQ) | baseline, during the intervention |
| blood glucose | fasting and pre-meal blood glucose | baseline, during the intervention |
| Measure | Description | Time Frame |
|---|---|---|
| dietary intake | food logs used to track food intake during all trial visits | during the intervention |
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Inclusion Criteria:
Exclusion Criteria:
male
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ohio University Exercise Physiology Lab | Athens | Ohio | 45701 | United States |
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| ID | Term |
|---|---|
| D011506 | Proteins |
| ID | Term |
|---|---|
| D000602 | Amino Acids, Peptides, and Proteins |
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Blinded pre-made packets of protein or placebo with sample coding in a sealed envelope until the end of the study