Long-term Mortality After Intensive Care Considering Como... | NCT06234709

Studies
Long-term Mortality After Intensive Care Considering Comorbidity and Admission Diagnoses

NCT06234709

Sponsor

Anna Aronsson

Status

Completed

Last Update Posted

Feb 2, 2024Actual

Enrollment

200,000Actual

Phase

Not provided

Conditions

Critical Care

Interventions

Not provided

Countries

Sweden

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Feb 2024

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 1, 2005Actual

Primary Completion Date

Dec 31, 2016Actual

Completion Date

Dec 31, 2016Actual

First Submitted Date

Jan 22, 2024

First Submission Date that Met QC Criteria

Jan 22, 2024

First Posted Date

Jan 31, 2024Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Feb 1, 2024

Last Update Posted Date

Feb 2, 2024Actual

Name	Class
Uppsala University	OTHER

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

This is a register-based study

The aim of this study is to investigate how common comorbidity is in different age groups and which comorbidity that has the greatest impact on mortality considering different admission diagnosis and after the acute phase compared to the general population. Also, how different degrees of comorbidity affect mortality, adjusted for other comorbidities and SAPS 3?

Detailed Description

The study population included all patients > 16 years old admitted to an ICU during the years 2006 to 2012 and registered in the Swedish Intensive Care Registry (SIR).

Hospital discharge diagnoses from in-patient care five years preceding the index time for the ICU admission were extracted from the National Patient Register (NPR) and linked to ICU admissions using unique person identity numbers. Follow-up for all-cause mortality were extracted from the cause of death register at NPR.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

200,000Actual

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
All-cause mortality	Extracted from the cause of death register at National Patient Registry in Sweden.	january 1, 2005 til december 31, 2016

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

The study population included all patients > 16 years old admitted to an ICU during the years 2006 to 2012 and registered in the Swedish Intensive Care Registry (SIR)

Exclusion Criteria:

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

16 Years

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

The study population included all patients > 16 years old admitted to an ICU during the years 2006 to 2012 and registered in the Swedish Intensive Care Registry (SIR)

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Anna Aronsson Dannewitz, med mag	Uppsala university department of surgical sciense	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Uppsala university department of surgical sciences		Uppsala		75310	Sweden

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
39543756	Derived	Aronsson Dannewitz A, Svennblad B, Michaelsson K, Lipcsey M, Gedeborg R. The long-term conditional mortality rate in older ICU patients compared to the general population. Crit Care. 2024 Nov 14;28(1):368. doi: 10.1186/s13054-024-05147-z.