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| ID | Type | Description | Link |
|---|---|---|---|
| 2026/1 | Other Identifier | Atatürk University Clinical Research Ethics Committee |
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This retrospective cohort study will evaluate whether syndromic clinical diagnoses present at ICU admission are associated with ICU mortality, independent of physiologic severity scores. Adult patients admitted to a tertiary mixed ICU during 2025 will be assessed.
Data will be obtained retrospectively from the hospital information system and ICU clinical records. Variables will be recorded based on the first 24 hours after ICU admission. Demographics, admission characteristics, comorbidities, severity scores (APACHE II, SAPS, SOFA), and admission syndromic diagnoses (e.g., sepsis/septic shock, acute respiratory failure, ARDS, MODS) will be collected. The primary outcome is ICU mortality; secondary outcomes include ICU length of stay and ICU discharge disposition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adult ICU admissions (2025) | Adult patients (≥18 years) admitted to a tertiary mixed intensive care unit between January 1, 2025 and December 31, 2025. For patients with multiple ICU admissions, only the first ICU admission will be included. Data will be abstracted retrospectively from electronic medical records and ICU charts; variables will be recorded based on the first 24 hours after ICU admission. |
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| Measure | Description | Time Frame |
|---|---|---|
| ICU mortality | Death occurring during the index ICU stay (ICU mortality), abstracted from electronic medical records. | From ICU admission until ICU discharge (end of index ICU stay), assessed up to 90 days |
| Measure | Description | Time Frame |
|---|---|---|
| ICU length of stay (LOS) | ICU length of stay (days) during the index ICU admission, calculated as the difference between ICU admission and ICU discharge timestamps in the electronic medical record. | From ICU admission to ICU discharge (index ICU stay), assessed at ICU discharge (up to 90 days) |
| ICU discharge disposition |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients admitted to the tertiary mixed ICU of Atatürk University Faculty of Medicine (Department of Anesthesiology and Reanimation) between January 1 2024 and December 31 2025. Data will be collected retrospectively from hospital information systems and ICU records, based on the first 24 hours after ICU admission.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ataturk University | Erzurum | 25240 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 8254858 | Background | Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA. 1993 Dec 22-29;270(24):2957-63. doi: 10.1001/jama.270.24.2957. | |
| 3928249 | Background | Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985 Oct;13(10):818-29. |
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Individual participant data will not be shared because the dataset is derived from retrospective hospital records and contains potentially identifiable information.
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| ID | Term |
|---|---|
| D016638 | Critical Illness |
| D018805 | Sepsis |
| D012772 | Shock, Septic |
| D012128 | Respiratory Distress Syndrome |
| D009102 | Multiple Organ Failure |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D007239 | Infections |
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Disposition at ICU discharge categorized as: death in ICU, transfer to hospital ward, or transfer to another facility; determined from the ICU discharge documentation in the electronic medical record. |
| At ICU discharge (index ICU stay; assessed at the time of ICU discharge in the medical record, up to 90 days) |
| 24256390 | Background | Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med. 2013 Nov 21;369(21):2063. doi: 10.1056/NEJMc1312359. No abstract available. |
| 24740011 | Background | Vincent JL, Marshall JC, Namendys-Silva SA, Francois B, Martin-Loeches I, Lipman J, Reinhart K, Antonelli M, Pickkers P, Njimi H, Jimenez E, Sakr Y; ICON investigators. Assessment of the worldwide burden of critical illness: the intensive care over nations (ICON) audit. Lancet Respir Med. 2014 May;2(5):380-6. doi: 10.1016/S2213-2600(14)70061-X. Epub 2014 Apr 14. |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D012769 | Shock |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D012120 | Respiration Disorders |