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The exploration of the safety and efficacy of fecal microbiota transplantation in the treatment of non-digestive system diseases associated with gastrointestinal symptoms in the gastrointestinal tract, while also investigating the impact of fecal microbiota transplantation on the intestinal system, and assessing the improvement of symptoms in other systems.Simultaneously optimizing the conditions during the FMT process, identifying the most effective treatment methods to enhance the therapeutic outcomes of FMT.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| FMT group | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Fecal microbiota transplantation | Procedure | Fecal microbiota transplantation (FMT) is a method for treating imbalances in the intestinal microbiota. Its basic principle involves extracting a portion of feces from a healthy individual that contains a diverse population of beneficial bacteria, processing it, and transplanting it into the digestive system of the recipient to restore a balanced intestinal microbiota. |
| Measure | Description | Time Frame |
|---|---|---|
| Comparing the therapeutic efficacy of patients after FMT. | Through conducting relevant questionnaire surveys with patients, we can gain insights into the therapeutic efficacy of patients after undergoing FMT. | 0day, 7days, 30days, 3 months, 6months,12 months |
| Comparing the differences in microbiota composition in samples such as feces and small intestinal fluid from patients. | Performing 16S rRNA sequencing, metagenomic sequencing, and metabolite analysis on the samples. | 0day, 7days, 30days, 3 months, 6months,12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Le Wang | Recruiting | Shanghai | Shanghai Municipality | 200040 | China |
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|
| ID | Term |
|---|---|
| D000069467 | Fecal Microbiota Transplantation |
| ID | Term |
|---|---|
| D001691 | Biological Therapy |
| D013812 | Therapeutics |
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