Rheumatic autoimmune diseases include conditions such as systemic lupus rheumatoid arthritis systemic sclerosis in which connective tissues are frequently targeted.

Autoimmune diseases as a group are among the leading causes of death and morbidity in the industrial world and pose an immense socioeconomic burden despite the considerable accumulative burden of these diseases only a small number of multinational registries for a few selected autoimmune diseases have been devised.

Numerous autoimmune inflammatory diseases have been associated with various forms of vasculopathy and increase vascular disease risk such as accelerated atherogenesis and thromboembolic events as digital and acral gangrene secondary Raynaud syndrome arterial aneurysm and different cutaneous ulcer.

The etiopathogenesis os increased risk of peripheral vascular diseases and presentation in autoimmune diseases is not entirely clear but multiple contibutors have been explored especially in the context of systemic inflammation and disordered thrombogenesis.

Inclusion Criteria:

• all ages
• Both sexes
• Recent or past history of vascular diseases or presentation in any proven autoimmune diseases according to the guidlines.

Exclusion Criteria:

• patients refuse the study
• patients do not have established diagnosis of vascular diseases .
• patients not completely approved to have autoimmune diseases.

• All ages
• Both sexes
• Recent or past history of vascular diseases or presentation in any proven autoimmune diseases according to the guidlines.