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| Name | Class |
|---|---|
| Assuta Medical Center | OTHER |
| Tel Aviv University | OTHER |
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In this prospective randomized sibling-oocytes blinded study, investigators examine the combination of two sperm selection methods that logically seem to complete each other, and potentially may improve ICSI outcomes.
The methods include the selection of the optimal spermatozoa based on its morphology by IMSI, together with its physiological function of binding to HA by Spermslow (SS).
The current study compared a group of ET after sperm selection by IMSI with SS to a group of ET after sperm selection by IMSI-only without SS, and to a mixed ET group where two embryos were transferred, one after IMSI-only and the other one after IMSI with SS.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The IMSI-only group | Active Comparator | The IMSI-only group |
|
| IMSI with SpermSlow group | Active Comparator | IMSI with SpermSlow group |
|
| Mixed embryo group | No Intervention | Mixed embryo group |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sperm selection by IMSI | Procedure | Intracytoplasmic morphologically selected sperm injection (IMSI) is a sperm selection method used in intracytoplasmic sperm injection (ICSI) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pregnancy and delivery rates | Pregnancy and delivery rates | Within up to 10 month from treatment |
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Inclusion Criteria:
females ages 38 or younger retrieval of at least 5 mature oocytes and fresh ejaculate samples
Exclusion Criteria:
frozen embryos surgically extracted sperm preparations embryo-biopsy cycles
Based on sperm and ovum during IVF procedure
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Meir Medical Center | Kfar Saba | Israel |
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| ID | Term |
|---|---|
| D007246 | Infertility |
| ID | Term |
|---|---|
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| Sperm selection by IMSI and spermslow | Procedure | Intracytoplasmic morphologically selected sperm injection (IMSI) is a sperm selection method used in intracytoplasmic sperm injection (ICSI) + spermslow |
|