A Comparative Study of Sibling Oocytes: ICSI vs. the IMSI Sperm Selection Method

A Comparative Study of Sibling Oocytes, Which Examines Two Sperm Selection Methods for Top Quality of Spermatozoa , Prior Intracytoplasmic Sperm Injection (ICSI) Performance, and Their Effect on Embryo Quality and IVF Outcome: A Common Selection Method Based on Morphology (ICSI) vs. an Ultra Morphology Section Method - Intracytoplasmic Morphology Selected Sperm Injection (IMSI)

The aim of this research is to compare sibling oocytes using two sperm selection methods for choosing the best quality spermatozoa before they are injected into oocytes and the influence of each of these methods on embryo quality and IVF outcome.

Inclusion Criteria:

• Males aged 18-60
• Females aged 18-35
• Males defined as Moderate OTA or Isolated Teratozoospermia with less than 4% morphologically normal spermatozoa
• Patients with 0.5- 7% normal sperm according to MSOME analysis
• Females with normal FSH and AMH values
• Females who have retrieved at least 6 oocytes in previous cycles
• Couples who have had at least 2 failed IVF-ICSI cycles

Exclusion Criteria:

• Couples who have been exposed to heavy smoking, drugs and chronic diseases
• Males who have undergone testicular surgery (TESE) or defined as severe OTA
• Females with egg factor infertility