Effect of TCI188 Probiotic on Oral Health | NCT06141083 | Trialant
CompletedInterventionalNot ApplicableUpdated Feb 4, 2026
Effect of TCI188 Probiotic on Oral Health
Effect of TCI188 Probiotic on Oral Health
ClinicalTrials.gov ID
NCT06141083
Lead Sponsor
TCI Co., Ltd.INDUSTRY
Overall Status
Completed
Study Type
Interventional
Phase
Not Applicable
Enrollment
55Actual
Last Update Posted
Feb 4, 2026Actual
Start Date
Nov 1, 2023Actual
Primary Completion Date
Dec 8, 2025Actual
Completion Date
Jan 30, 2026Actual
Official Title
Effect of TCI188 Probiotic on Oral Health
Brief Summary
To assess the efficacy of TCI188 (Pediococcus acidilactici) Probiotic on Oral Health
Periodontal Diseases
TCI188 Probiotic
Placebo
Ages Eligible for Study
Adult (18-64)Older Adult (65+)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
Yes
Eligibility Criteria
Inclusion Criteria:
Male or female over 18 years old
Participants suffer from severe periodontal disease throughout the mouth with symptoms at third and fourth stages, do not have immediate indications for the extraction of multiple teeth or complex denture stimulation, and have not undergone periodontal planing within one year.
Exclusion Criteria:
Participants have had periodontal or antimicrobial treatment within the past 6 months
Participants are smokers, pregnant or with systemic diseases
Participants had probiotic supplements or with history of adverse reactions to lactose or fermented dairy products