Double-blind Clinical Trials of Probiotic Products in Oral Health.

Double-blind Clinical Trials of Probiotic Products in Oral Health.

In order to evaluate the effects of supplementary probiotics and their metabolites on oral environment and oral microbiota, Taiwan FDA No. 88037803 will be used to evaluate the effects of oral probiotic candidate strains from previous research results and develop oral probiotic products.

Inclusion Criteria:

• Adults between 20 to 40 years old.
• More than 10^5 Streptococcus mutans (CFU/mL) of saliva.

Exclusion Criteria:

• Smoking.
• Subject has major illness.