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| ID | Type | Description | Link |
|---|---|---|---|
| 1R01AA030678-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| University of Texas | OTHER |
| National Institute on Alcohol Abuse and Alcoholism (NIAAA) | NIH |
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The goal of this clinical trial (CT) is to learn more about emerging adults' and their peers. Here, we will see how co-participating with a peer in health program might impact brain and behavior change over time.
Eligible youth will be invited to come in for a "Participation Day," during which they and a peer will independently complete questionnaires. With a peer, they will then complete a short health program, and undergo a brain scan (fMRI) while completing activities. Our study team will reach out to each participant individually again 3, 6, and 12 months later to learn about health behaviors over time.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Motivational Interviewing (MI) | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Motivational Interviewing (MI) | Behavioral | Motivational interviewing with peer dyads starts with an open-ended exploration of the dyad's hazardous drinking behavior via personal stories about alcohol use. It includes a values clarification task and age-matched norms along with personalized feedback regarding the dyad's alcohol use. The goal of the session is to engage the dyad in a thoughtful conversation about drinking and the implications it may have on their lives, with an eye to bolstering and supporting inherent drive for behavior change. |
| Measure | Description | Time Frame |
|---|---|---|
| Blood oxygen level dependent (BOLD) response synchrony | Mean BOLD time series will be obtained for each region of interest (ROI) during peer-directed change talk trials and temporally aligned across dyad participants. Inter-brain synchrony will be quantified using z-transformed GLM β-weights within ROIs between the BOLD time series of dyad members. | Baseline |
| BOLD response synchrony association with behavior change (past month alcohol use days) | Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 12 month follow up. | 12 Months |
| Measure | Description | Time Frame |
|---|---|---|
| BOLD response synchrony association with behavior change (past month alcohol use days) | Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 3 month follow up. | 3 Months |
| BOLD response synchrony association with behavior change (past month alcohol use days) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Karen Hudson, MCR | Contact | 860-679-1037 | khudson@uchc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Sarah W. Feldstein Ewing, PhD | UConn Health | Principal Investigator |
| Francesca Filbey, PhD | University of Texas | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Texas Dallas | Recruiting | Dallas | Texas | 75235 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42275392 | Derived | Feldstein Ewing SW, Dash GF, Hudson KA, Hyun B, Yang M, Stahl L, Thomsen KR, Filbey FM. The Protocol for: Do peers enhance behavior change in group motivational interviewing? A translational clinical trial investigating brain synchrony in underage emerging adults during an fMRI hyperscanning task and association with alcohol use reductions. PLoS One. 2026 Jun 11;21(6):e0349575. doi: 10.1371/journal.pone.0349575. eCollection 2026. |
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This study will submit and share data with the NIAAA Data Archive, a data repository housed within the NIMH Data Archive, and will follow the guidelines described in NOT-AA-23-002.
Data will be submitted on or before the NDA submission due dates and maintained for the duration required by NIAAA Data Archive Data Sharing Plan.
See details provided by the NIAAA Data Archive.
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| ID | Term |
|---|---|
| D000428 | Alcohol Drinking |
| ID | Term |
|---|---|
| D004327 | Drinking Behavior |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D062405 | Motivational Interviewing |
| ID | Term |
|---|---|
| D037001 | Directive Counseling |
| D003376 | Counseling |
| D008605 | Mental Health Services |
| D004191 | Behavioral Disciplines and Activities |
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Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 6 month follow up. |
| 6 Months |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |