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The goal of this interventional study is to learn about the effects of different proteins (from animals or plants) on the metabolism in healthy, normal weight women between 18-45 year who are not on hormonal birth-control.
The main questions the study aims to answer are:
Participants will drink four different shakes on four different study days in a random order. Three of them contain each a different protein and one does not contain protein. Right before drinking the shake and on 11 timepoints after drinking the shake blood samples will be drawn.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Isolated Pea Protein/Isolated Whey Protein/Isolated Faba Bean Protein/Placebo | Experimental |
The fat and energy content of the drinks will be adapted using a plant based oil |
|
| Isolated Whey Protein/Placebo/Isolated Pea Protein/Isolated Faba Bean Protein | Experimental |
The fat and energy content of the drinks will be adapted using a plant based oil |
|
| Isolated Faba Bean Protein/Isolated Pea Protein/Placebo/Isolated Whey Protein | Experimental |
The fat and energy content of the drinks will be adapted using a plant based oil |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Isolated Pea Protein | Dietary Supplement | Participants will consume the protein supplement dissolved in water in an opaque mug wearing a nose clip. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Release of Growth Hormone | The primary outcome is defined as the postprandial release of growth hormone during three hours after oral ingestion of plant-protein test drinks vs. an animal-protein test drink measured as incremental area under the curve. Growth hormone will be measured in blood samples. | 0-3 hours after consumption of test drink (on all 4 study days) |
| Measure | Description | Time Frame |
|---|---|---|
| Release of Hormones Related to the Somatotrophic Axis | We will measure different hormones related to the somatotrophin axis in collected blood samples and investigate if there are differences between different protein-sources. | 0-3 hours after consumption of test drink (on all 4 study days) |
| Kinetics of Amino Acid Uptake |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Örebro University | Örebro | 70182 | Sweden |
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| Placebo/Isolated Faba Bean Protein/Isolated Whey Protein/Isolated Pea Protein | Experimental |
The fat and energy content of the drinks will be adapted using a plant based oil |
|
| Isolated Whey Protein | Dietary Supplement | Participants will consume the protein supplement dissolved in water in an opaque mug wearing a nose clip. |
|
| Isolated Faba Bean Protein | Dietary Supplement | Participants will consume the protein supplement dissolved in water in an opaque mug wearing a nose clip. |
|
| Placebo | Dietary Supplement | Participants will consume the placebo in an opaque mug wearing a nose clip. |
|
We will measure amino acids in collected blood samples to investigate dynamics and kinetics of protein digestion/uptake of different protein sources. |
| 0-3 hours after consumption of test drink (on all 4 study days) |