Feasibility of Integrated Care of Depression in Primary Care Pathways

Evaluation de Soins Primaires Intégrés en Psychiatrie

This protocol is a feasibility study of an integrated primary care pathway for patients suffering from difficult-to-treat depression. 50 patients will be recruited and followed for two years.

Inclusion Criteria:

• age 18-65 years
• Good understanding of french language
• Major depressive disorder based on DSM-V criteria
• MADRS > 19
• FAilure of two antidepressants during 6wks at standard minimal dose

Exclusion Criteria:

• Pregnancy or lactating
• People under tutelage
• bipolar disorder
• no health insurance
• neurological disorders
• contra-indication to physical activity
• high suicidal risk
• first degree history of bipolar disorder, schizophrenia, autism spectrum disorder