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The aim of this study is to collect clinical data and biological specimens from patients with myocarditis and construct a predictive model for the prognosis of myocarditis.
The aim of this study is to retrospectively and prospectively collect clinical data and biological specimens from patients with myocarditis who meet the inclusion and exclusion criteria. General molecular biology analysis, genome sequencing, transcriptome sequencing, methylation sequencing, metabolomics analysis, proteomics analysis, genome-wide chromosome conformation capture and other techniques are used to construct a prognosis prediction model for myocarditis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Myocarditis group | All enrolled patients are administered antiviral drugs, glucocorticoids, immunoglobulins, and other standard treatments. Additionally, the decision to provide ECMO support therapy is based on the severity of the patient's condition. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in the incidence of MACCE | MACE (major adverse cardiovascular events) including all-cause death, myocardial infarction, stroke and coronary revascularization surgery. The MACCE will be assessed from the medical records. | 1, 3, 6 months after enrollment; and 1, 2, 3, 4, 5 years after enrollment. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in the incidence of all-cause death | All-cause death diagnosed by clinical doctors will be assessed from the medical records | 1, 3, 6 months after enrollment; and 1, 2, 3, 4, 5 years after enrollment. |
| Change in the incidence of myocardial infarction |
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Inclusion Criteria:
Exclusion Criteria:
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All hospitalized patients who meet the diagnostic criteria for myocarditis and undergo regular follow-up at the corresponding cardiovascular center are included in the study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guoliang Li | Contact | +8613759982523 | liguoliang_med@163.com | |
| Yang Yan | Contact | +8613259882601 | yangyan3@xjtu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Yang Yan | First Affiliated Hospital Xi'an Jiaotong University | Principal Investigator |
| Guoliang Li | First Affiliated Hospital Xi'an Jiaotong University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| First Affiliated Hospital of Xi'an Jiaotong University | Recruiting | Xi'an | Shaanxi | 710061 | China |
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| ID | Term |
|---|---|
| D009205 | Myocarditis |
| ID | Term |
|---|---|
| D009202 | Cardiomyopathies |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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Blood, urine, feces.
Myocardial infarction diagnosed by clinical doctors will be assessed from the medical records |
| 1, 3, 6 months after enrollment; and 1, 2, 3, 4, 5 years after enrollment. |
| Change in the incidence of stroke | Stroke diagnosed by clinical doctors will be assessed from the medical records | 1, 3, 6 months after enrollment; and 1, 2, 3, 4, 5 years after enrollment. |
| Change in the incidence of coronary revascularization surgery | Coronary revascularization surgery completed by clinical doctors will be assessed from the medical records | 1, 3, 6 months after enrollment; and 1, 2, 3, 4, 5 years after enrollment. |