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Explore the imaging and quantitative monitoring of hip bone, cartilage and ligament by magnetic resonance UTE technology, combined with QCT and DXA technology, to provide a more accurate basis for clinical evaluation and treatment.
Osteoporosis is a systemic bone metabolism-related disease characterized by decreased bone mass per unit volume, increased bone fragility, decreased bone density, thinning of the bone cortex and changes in bone microstructure. It often occurs in the lumbar spine and hip joint. Femoral neck fracture is a common complication of hip osteoporosis, which seriously affects people's quality of life. UTE technology can clearly image and quantify human cortical bone and cancellous bone, and advanced UTE technology such as STAIR-UTE and UTE-MT have made some progress in the field of osteoporosis. The purpose of this study was to explore UTE technology for imaging and quantitative study of cortical bone, cancellous bone and cartilage of hip joint, and to find more accurate imaging methods for clinical evaluation of hip osteoporosis and other diseases.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| normal group | There are no lesions on the hip. | ||
| abnormal group | There are some lesions on the hip. |
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| Measure | Description | Time Frame |
|---|---|---|
| proton density fat fraction (PDFF) | Magnetic resonance proton density fat fraction | Baseline (before surgery) |
| T2 relaxation rate | R2* | Baseline (before surgery) |
| Magnetization Transfer Ratio (MTR) | magnetization transfer ratio | Baseline (before surgery) |
| T1rho | spin-lattice relaxation in the rotation ame | Baseline (before surgery) |
| Measure | Description | Time Frame |
|---|---|---|
| Subjective rating values | rating values | Baseline (before surgery) |
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Inclusion Criteria:
Exclusion Criteria:
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Patients who meet the inclusion criteria
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xiaojun Chen | Contact | +8615820587112 | 422175400@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Shaolin Li | Fifth Affiliated Hospital, Sun Yat-Sen University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Radiography department | Recruiting | Zhuhai | Guangdong | 519000 | China |
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