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Quantitative characteristic values of lung lesions were obtained by UTE technique, so as to make qualitative diagnosis of benign and malignant lesions. And to explore the clinical feasibility of CT-like technology - high resolution ZTE technology in the diagnosis of pulmonary diseases.
Ultrashort echo time (UTE) sequence can obtain data from T2* for lung imaging before T2* decays in lung parenchyma with extremely short echo time, which makes up for the defect that conventional MRI cannot clearly display short T2 tissue imaging, and can provide more supplementary information for lung CT scan. There has been a lot of research progress in the evaluation of neonatal lung disease, chronic obstructive airway disease and pneumonia. The 3D UTE sequence developed on this basis has made great progress in improving the resolution, signal-to-noise ratio and shortening the scanning time of lung MR Images, and has successfully obtained submillimeter high-resolution images. The purpose of this study was to explore the value of MRI ultra-short echo technology in the qualitative diagnosis of benign and malignant lung lesions, and to explore the clinical application of CT-like technology - high resolution ZTE technology in the lung.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| benign group | benign lesions in the lung | ||
| malignant group | malignant tumor in the lung |
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| Measure | Description | Time Frame |
|---|---|---|
| proton density fat fraction (PDFF) | Determination of proton density fat fraction by magnetic resonance imaging | baseline (before surgery) |
| T2 relaxation rate | R2* | baseline (before surgery) |
| Magnetization Transfer Ratio (MTR) | Magnetization Transfer Ratio | baseline (before surgery) |
| Measure | Description | Time Frame |
|---|---|---|
| Subjective rating | rating scale | baseline (before surgery) |
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Inclusion Criteria:
Exclusion Criteria:
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People who meet the inclusion criteria.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xiaojun Chen | Contact | +8615820587112 | 422175400@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Shaolin Li | Fifth Affiliated Hospital, Sun Yat-Sen University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Radiography department | Recruiting | Zhuhai | Guangdong | 519000 | China |
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| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| ID | Term |
|---|---|
| D012140 | Respiratory Tract Diseases |
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