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To assess Hibiscus sabdariffa extract and collagen products on skin condition improvement
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo sachet | Placebo Comparator |
| |
| Hibiscus sabdariffa extract and collagen products | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo sachet | Dietary Supplement | Consume 1 sachet daily |
| |
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin collagen density | DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units | Week 0, week 4, week 8 |
| The change of skin wrinkles | VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units | Week 0, week 4, week 8 |
| The change of skin texture | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units | Week 0, week 4, week 8 |
| The change of skin elasticity | SoftPlus was utilized to measure skin elasticity. Units: arbitrary units | Week 0, week 4, week 8 |
| The change of skin moisture | Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120 | Week 0, week 4, week 8 |
| Measure | Description | Time Frame |
|---|---|---|
| The change of skin melanin index | Mexameter® MX18 was utilized to measure skin melanin index. Units: arbitrary units | Week 0, week 4, week 8 |
| The change of skin L* value | Chroma Meter MM500 was utilized to measure skin L* value. Units: arbitrary units, 0-100 |
| Measure | Description | Time Frame |
|---|---|---|
| The change of self-assessment skin condition | A self-assessment questionnaire was collected to evaluate skin condition | Week 0, week 4, week 8 |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chia-Hua Liang | Chia Nan University of Pharmacy ＆ Science | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chia Nan University of Pharmacy ＆ Science | Tainan | Taiwan |
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| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| ID | Term |
|---|---|
| D017437 | Skin and Connective Tissue Diseases |
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| Hibiscus sabdariffa extract and collagen products |
| Dietary Supplement |
Consume 1 sachet daily |
|
|
| Week 0, week 4, week 8 |
| The change of transepidermal water loss (TEWL) | Tewameter® TM 300 was utilized to measure TEWL. Units: g/hm² | Week 0, week 4, week 8 |
| The change of skin pores | VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units | Week 0, week 4, week 8 |
| The change of skin spots | VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units | Week 0, week 4, week 8 |