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This study assess the ways in which e-cigarette product characteristics, such as flavors and nicotine salts, impact user experience to inform potential regulations.
There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| E-Liquid 1 | Experimental | Participants will self-administer an assigned e-liquid. |
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| E-Liquid 2 | Experimental | Participants will self-administer an assigned e-liquid. |
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| E-liquid 3 | Experimental | Participants will self-administer an assigned e-liquid. |
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| E-liquid 4 | Experimental | Participants will self-administer an assigned e-liquid. |
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| No e-liquid | No Intervention | Participants will not receive an e-liquid to self-administer. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| E-cigarette | Other | Participants will self-administer experimenter-provided e-cigarettes |
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| Measure | Description | Time Frame |
|---|---|---|
| Subjective Appeal | This self-report measures of subjective product appeal will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the appeal rating, with lower scores representing lower levels of appeal and higher scores representing higher levels of appeal. | 1 hour |
| Sensory Attributes | This self-report measures of product sensory attributes will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the sensory attribute rating, with lower scores representing lower levels of liking the sensory attribute and higher scores representing greater liking of the sensory attribute. | 1 hour |
| Vaping Delay | Minutes delayed before purchasing time to vape an e-liquid. | 1 hour |
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Inclusion Criteria:
Vapers/E-cigarette Users - Regular use of e-cigarettes/vaping devices containing nicotine
Cigarette Smokers
- Regular use of cigarettes containing nicotine
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Southern California | Los Angeles | California | 90033 | United States |
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| ID | Term |
|---|---|
| D000072137 | Vaping |
| D000073865 | Cigarette Smoking |
| ID | Term |
|---|---|
| D012907 | Smoking |
| D001519 | Behavior |
| D000073869 | Tobacco Smoking |
| D064424 | Tobacco Use |
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| ID | Term |
|---|---|
| D066300 | Electronic Nicotine Delivery Systems |
| ID | Term |
|---|---|
| D000074602 | Smoking Devices |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |
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Participants will be randomly assigned to use an e-liquid
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