Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Prachi Singh | UNKNOWN |
| Frank L. Greenway | UNKNOWN |
| Robbie A. Beyl | UNKNOWN |
Not provided
Not provided
Not provided
Not provided
The objective of this study is to assess the effects of Hass Avocados on glycemic control. The investigators hypothesize that Hass Avocado consumption will reduce fasting blood sugar compared to an isocaloric amount of other fruit during controlled feeding.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Avocado | Experimental | Participants will consume 1 Hass avocado a day. |
|
| Other Fruit(s) | Active Comparator | Participants in the other fruit arm will receive other fruits. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Avocado | Other | The Hass Avocado group will consume 7 avocados a week (1 / day; ~240 kcals/d). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Fasting Blood Glucose | the primary outcomes are based on within subject concentration change scores | Week 5 - Week 0 |
| Measure | Description | Time Frame |
|---|---|---|
| Fasting Insulin | within subject concentration change scores | Week 5 - Week 0 |
| Fructosamine | within subject concentration change scores |
| Measure | Description | Time Frame |
|---|---|---|
| Blood Glucose | Continuous Glucose Monitoring | Week 5 - Week 0 |
| Glucose | Oral Glucose Tolerance Test (OGTT) | Week 5 - Week 0 |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| John W Apolzan, PhD | Contact | 2257632827 | John.Apolzan@pbrc.edu | |
| Rob Leonard | Contact | 2257630948 | doctors@pbrc.edu |
| Name | Affiliation | Role |
|---|---|---|
| John W Apolzan, PhD | Pennington Biomedical Research Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pennington Biomedical Research Center | Recruiting | Baton Rouge | Louisiana | 70808 | United States |
Data may be requested. The PI and sponsor will be notified. The proposed research question must be included. All IPD that underlie results in a publication after a DTA with the institution.
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| D007333 | Insulin Resistance |
| D050177 | Overweight |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
Not provided
Not provided
This study utilizes a randomized crossover design with each period/treatment being approximately 5 weeks. Participants will be randomized to either Hass Avocado or other fruit(s) consumption groups. The treatments will be isocaloric as will the Hass Avocado vs. the other fruit(s). All subjects will consume a diet provided by the metabolic research kitchen. The diet will be matched on energy (kcal).
Not provided
Not provided
The investigators and outcome assessors will be blinded to study treatment.
| Other Fruit(s) | Other | The other fruits group will consume fruit(s) matched to the avocado in energy and form (i.e., solid fruit). |
|
|
| Week 5 - Week 0 |
| Glycated Albumin | within subject concentration change scores | Week 5 - Week 0 |
| Insulin | Oral Glucose Tolerance Test (OGTT) | Week 5 - Week 0 |
| D004700 | Endocrine System Diseases |
| D006946 | Hyperinsulinism |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |