Neurological Blood-based Biomarkers and Cognitive Disorders in Critically Ill Survivors.

The Relationship Between Neurological Blood-based Biomarkers and Mid-term Cognitive Disorders in Critically Ill Survivors.

Cognitive disorders are common after intensive care. Currently, their diagnosis is based on clinical tests. The investigators plan to study the relationship between different neurological blood biomarkers (cytokines, S100β protein, neuron specific enolase, total Tau protein and neurofilament light chain) and the occurrence of cognitive disorders during the three months following intensive care discharge.

Inclusion Criteria:

• Anticipated ICU stay of at least 7 days for sepsis, acute respiratory distress syndrome, severe burns
• French speaking

Exclusion Criteria:

• hearing loss or blindness
• mental retardation
• known cognitive disorders or dementia
• ICU admission for neurological disease
• refusal