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The goal of this randomized clinical trial study is to compare low-load blood flow restriction (LL-BFRt), sham LL-BFRt, and high-load eccentric training (HL-Et) in healthy level 1 sportsman. The main questions it aims to answer are:
Participants will be randomized into three intervention groups: LL-BFRt, sham LL-BFRt, and HL-Et. Participants will be asked to do:
Researchers will compare LL-BFRt, sham LL-BFRt, and HL-Et to see if muscle strength, dynamic stability, and ACL injury prevention improve after the interventions and follow-up.
Participants will be asked to do five sets of ten repetitions of each eccentric training, one-minute rest interval for each eccentric training and two mins rest interval between each set.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| LL-BFRt | Experimental | 30% of repetition maximum and 70% of arterial occlusion pressure |
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| Sham LL-BFRt | Sham Comparator | 30% of repetition maximum and 10% of arterial occlusion pressure |
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| HL-Et | Active Comparator | 70% of repetition maximum |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low-load Blood Flow Restriction training | Procedure | Physical therapist will apply the BFR cuffs with 70% of arterial occlusion pressure on the both legs of participants. Then, participants will be asked to perform eccentric trainings (including, double leg squats, split squats, deadlifts, and monster walks) with 30% of repetition maximum. |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle strength | Investigators will measure the quadriceps muscle isometric strength using dynamometer (units: Newton or kilogram). | 8 weeks |
| Dynamic stability I | Investigators will measure the dynamic stability I using Y-balance test (units: centimeter). | 8 weeks |
| Dynamic stability II | Investigators will measure the dynamic stability II using single leg hop test (units: centimeter). | 8 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Physical therapy laboratory, College of Medicine, Universitas Udayana and ROM Physiotherapy Private Clinic Denpasar | Denpasar | Bali | 80232 | Indonesia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39932234 | Derived | Adhitya IPGS, Aryana IGNW, Kurniawati I, Thanaya SAP, Utama MBR. Effect of Low-Load Blood Flow Restriction Training and High-Load Resistance Training on Quadriceps Strength, Dynamic Stability, and Functional Performance. Clin J Sport Med. 2026 Mar 1;36(2):111-119. doi: 10.1097/JSM.0000000000001330. Epub 2025 Feb 11. |
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| Sham Low-load Blood Flow Restriction training | Procedure | Physical therapist will apply the BFR cuffs with 10% of arterial occlusion pressure on the both legs of participants. Then, participants will be asked to perform eccentric trainings (including, double leg squats, split squats, deadlifts, and monster walks) with 30% of repetition maximum. |
|
| High-load Eccentric training | Procedure | Physical therapist will ask participants to perform eccentric trainings (including, double leg squats, split squats, deadlifts, and monster walks) with 70% of repetition maximum. |
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