Post hoc power analysis results on the primary hypothesis during the preliminary analyses

The main objective is to measure the effects of intense brief exercise program in the workplace of administrative staff on the cardio-metabolic health

Backgrounds: Very short (< 1 minute) and intense exercises, entitled "exercise-snacks", have been reported to be effective 1) in improving physical fitness over 6 weeks and 2) in improving vascular function and lowering blood glucose levels over one day. These studies were all carried out in the laboratory. The question therefore arises as to whether these acute vascular and metabolic benefits, as well as those on physical fitness, are sustainable over time following a chronic "exercise-snacks" program applicable in the professional environment to sedentary, overweight people.

Aims of this project is therefore to measure the effects of an "exercise-snacks" type physical activity program in the workplace of administrative staff on the cardio-metabolic health and sedentary behaviour of staff.

Inclusion Criteria:

• administrative staff,
• age between 30 and 60,
• body mass index ≥25kg/m²,
• sedentary time ≥7h/day,
• minimum 3 working days on site,
• no known cardiovascular or metabolic pathology, social security affiliation or benefit,
• ability and willingness to give free, written and informed consent.

Exclusion Criteria:

• pregnant or breast-feeding women,
• anti-hypertensive treatment, beta-blockers and anti-diabetics,
• known contraindications to physical activity (articular, cardiac or other),
• exercise-induced asthma,
• lack of motivation of subjects posing problems of compliance and adherence to the exercise program,
• participation in a study in the preceding 3 months, ongoing participation in a clinical trial.