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The present study aims to evaluate the clinical and radiographic success of premixed bio-ceramic MTA versus calcium hydroxide in indirect pulp capping of young permanent molars.
Researchers are still in search of an ideal material for pulp capping, and they evaluated numerous dental materials. For many decades, calcium hydroxide has been the 'gold standard' material for maintaining pulp vitality. Both clinically and histologically, it has been found to produce satisfactory results in indirect and direct pulp capping because it can stimulate the formation of tertiary dentine by the pulp and it has antimicrobial properties.
Due to the drawbacks of calcium hydroxide, several materials have been developed, such as NeoPUTTY which is premixed bio-ceramic Mineral Trioxide Aggregate (MTA) that triggers hydroxyapatite. Its firm, non-tacky consistency, wash-out resistance, and bioactivity make it a pediatric dentists' preferred material for every pulp need. It also delivers ready-to-use material for immediate placement with zero waste, saving cost and chair time.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Premixed Bio-ceramic MTA | Experimental | Partial caries removal will be carried out then Premixed Bio-ceramic MTA will be applied as indirect pulp capping agent followed by Glass ionomer filling and composite restoration |
|
| Calcium hydroxide | Active Comparator | Partial caries removal will be carried out then calcium hydroxide will be applied as indirect pulp capping agent followed by Glass ionomer filling and composite restoration |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Premixed Bio-ceramic MTA | Drug | Partial caries removal will be carried out then Premixed Bio-ceramic MTA will be applied as indirect pulp capping agent followed by Glass ionomer filling and composite restoration |
| Measure | Description | Time Frame |
|---|---|---|
| Immediate Postoperative pain | post operative pain by Verbal analogue scale.It is a 10 cm long horizontal line with points labeled from 0 to 10 where (0) indicates no pain, (1-3) mild pain, (4-6) moderate pain, and (7-10) severe pain. | one week |
| Measure | Description | Time Frame |
|---|---|---|
| The thickness of newly formed dentin | The thickness of newly formed dentin will be assessed in Mm through Digora software | 3,6,9,12 month |
| Soft tissue pathology | Swelling, sinus tract, fistula, mobility and pain on percussion will be assessed by clinical examination either present or not (binary) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Aya Ad Hamza, Phd | Contact | 01062315566 | aya.adel@dentistry.cu.edu.eg | |
| Sara Ah Mahmoud, Professor | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Aya Ad Hamza, Phd | Cairo University | Principal Investigator |
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IPD can be shared with citation to the investigator but not personal data of the patients to protect confidentiality.
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| ID | Term |
|---|---|
| D002126 | Calcium Hydroxide |
| C025702 | Dycal |
| ID | Term |
|---|---|
| D006878 | Hydroxides |
| D000468 | Alkalies |
| D007287 | Inorganic Chemicals |
| D017610 | Calcium Compounds |
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Randomized controlled trial
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|
| Calcium hydroxide | Drug | Partial caries removal will be carried out then calcium hydroxide will be applied as indirect pulp capping agent followed by Glass ionomer filling and composite restoration |
|
|
| 3,6,9,12 month |
| Radiographic changes | Radiolucency at the periapical or furcation area and Internal or external root resorption will be assessed through a digital periapical intraoral radiograph either present or not ( Binary) | 3,6,9,12 month |
| D000838 |
| Anions |
| D007477 | Ions |
| D004573 | Electrolytes |