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Conservative approaches such as indirect pulp capping techniques became popular over the last years for the management of deep carious lesions. In particular, indirect pulp-treatment (IPT) techniques have gained remarkable attention in pediatric dentistry, mainly because children require a fast and accurate treatment, besides it enables the affected primary tooth to remain in the mouth until exfoliation without causing any pain or infection.
Indirect pulp treatment is recommended for teeth with deep caries approximating the pulp with no signs and symptoms of pulp deterioration. In this treatment, the deepest layer of the remaining carious dentine (affected dentin) is covered with biocompatible material followed by an airtight restoration to achieve a good seal against microleakage, without the need to reencounter for the removal of remaining caries.
Calcium hydroxide has served as a gold standard for IPT over the years. However, the introduction of newer bioactive materials such as mineral trioxide aggregate (MTA) and Biodentine helped surpass the demerits of calcium hydroxide such as internal resorption, nonadherence to dentin, degradation over time, tunnel defects, and poor sealing ability.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| indirect pulp treatment with NeoPUTTY MTA | Experimental |
| |
| indirect pulp treatment with calcium hydroxide | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| NeoPUTTY MTA | Drug | NeoPUTTY, a premixed bioactive bioceramic MTA that triggers hydroxyapatite and supports healing |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinical success in term of the absence of post-operative pain | Visual analog scale | one year |
| Clinical success in term of the absence of pain on percussion, swelling, sinus, or fistula | Visual and clinical examinations | one year |
| Measure | Description | Time Frame |
|---|---|---|
| Radiographic success in term of the absence of any adverse radiographic findings (eg. internal or external root resorption or other pathologic changes | Radiographic examination | one year |
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Inclusion Criteria:
• Presence of active carious lesions involving either occlusal or proximal surfaces of primary molars.
Exclusion Criteria:
• History of spontaneous sharp, penetrating pain, or tenderness on percussion
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| marwa aly elchaghaby, phd | Contact | 01006231612 | marwaaly2003@yahoo.com |
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| ID | Term |
|---|---|
| D002126 | Calcium Hydroxide |
| ID | Term |
|---|---|
| D006878 | Hydroxides |
| D000468 | Alkalies |
| D007287 | Inorganic Chemicals |
| D017610 | Calcium Compounds |
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| calcium hydroxide | Drug | Calcium hydroxide the gold standard for IPT |
|
| D000838 |
| Anions |
| D007477 | Ions |
| D004573 | Electrolytes |