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The aim of this study is to find the utility of red cell distribution width and lactate/albumin ratio as prognostic markers in sepsis and septic shock patients.
Several indicators are being used to predict the prognosis of sepsis. Commonly used prognostic indicators include Acute Physiological and chronic health evaluation II (APACHE II), Sequential Organ Failure Assessment (SOFA), Mortality in Emergency Department Score (MEDS), New York Sepsis severity score.
Red cell distribution Width and lactate albumin ratio are being investigated for there prognostic value in septic patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non survivors group | At 28 day, patients were divided into Non survivors group and Survivors group. |
| |
| Survivors group | At 28 day, patients were divided into Non survivors group and Survivors group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Red cell distribution width | Diagnostic Test | Blood will be drawn from the peripheral vein, arterial or a central catheter. This procedure will be done at diagnosis, 3 ,7, 14 and 21 days of sepsis |
| Measure | Description | Time Frame |
|---|---|---|
| The prediction of mortality | The diagnostic accuracy for prediction of 28th day mortality by Red cell distribution Width and lactate albumin ratio. | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Length of intensive care stay | Length of intensive care stay from admission till discharge either to the ward or mortality. | 28 days or till discharge from intensive care. |
| Extent of organ dysfunctions in patients with severe sepsis and septic shock |
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Inclusion Criteria:
Exclusion Criteria:
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All patients of both sex with age between (18:60) years old admitted to surgical intensive care unit suffering from sepsis or septic shock will be enrolled in the study after fulfillments of inclusion and exclusion criteria.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shimaa S Awd, MBBCh | Contact | +20 101 011 6084 | shimaa_saad@med.tanta.edu.eg |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tanta University Hospitals | Tanta | Elgharbia | 31527 | Egypt |
The data will be available upon reasonable request from the corresponding author from one year after study completion
From one year after study completion
The data will be available upon reasonable request from the corresponding author
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| ID | Term |
|---|---|
| D018805 | Sepsis |
| D012772 | Shock, Septic |
| ID | Term |
|---|---|
| D007239 | Infections |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
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| ID | Term |
|---|---|
| D004909 | Erythrocyte Indices |
| ID | Term |
|---|---|
| D006403 | Hematologic Tests |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| lactate albumin ratio measurement | Diagnostic Test | Blood will be drawn from the peripheral vein, arterial or a central catheter. This procedure will be done at diagnosis, 3 ,7, 14 and 21 days of sepsis |
|
Organ dysfunction can be confirmed by acute change in sepsis-related organ failure assessment (SOFA).
| 28 days |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D012769 | Shock |
| D008919 | Investigative Techniques |
| D001790 | Blood Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |