Postoperative Pain Relieve for Patients Undergoing Surgical Treatment of Femoral Fracture

Risk-benefit Analysis of Intrathecal Morphine Administration to Patients Undergoing Surgical Treatment of Proximal Femoral Fracture (Monocentric, Single-blinded, Randomized Clinical Study Compared to Standard Treatment)

The aim of the study is to investigate postoperative pain relief for patients undergoing surgical treatment of proximal femoral fracture using intrathecal administration of morphine.

In this study, the investigators will compare the efficiency of intrathecal morphine administration with the standard of care (parenteral application of analgesics) for pain relief in patients after proximal femoral fracture surgery. The secondary outcome measure will be to determine the frequency of adverse effects of intrathecally administered morphine. The study will be monocentric, randomized, and single-blinded. A total of 50 patients are expected to be enrolled.

Inclusion Criteria:

• signed informed consent
• 60 to 90 years of age
• surgical treatment of proximal femur fracture
• The American Society of Anesthesiologists (ASA) classification I to III
• spinal anesthesia used for the operation

Exclusion Criteria:

• general anesthesia used for the operation
• allergy to opioids
• high risk of respiratory depression