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Falls are a common problem in elderly patients resulting fractured femur, which require early operation. Adequate postoperative pain control will provide good recovery. The investigators will compare the efficacy of postoperative pain control among intrathecal morphine, femoral nerve block, and periarticular infiltration with bupivacaine in patients undergone intramedullary hip screw under spinal anesthesia.
Study methods :
Every patients without any exclusion criteria will be performed spinal anesthesia by 0.5% heavy bupivacaine then divided into 4 groups
All patients will receive postoperative intravenous patient controlled analgesia (IV PCA) morphine for 48 hours.
Data collection
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Controlled group | No Intervention | Spinal anesthesia with 0.5% bupivacaine alone |
|
| Femoral nerve block | Active Comparator | Spinal anesthesia plus femoral nerve block with 20 mL of 0.25% bupivacaine |
|
| Intrathecal morphine | Active Comparator | Spinal anesthesia plus 0.1 mg of intrathecal morphine |
|
| Periarticular bupivacaine infiltration | Active Comparator | Spinal anesthesia plus periarticular infiltration with 20 mL of 0.25% bupivacaine |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bupivacaine, morphine | Drug | 1.8-2.5 mL of 0.5% heavy bupivacaine for spinal anesthesia 20 mL of 0.25% bupivacaine for femoral nerve block 0.1 mg of intrathecal morphine 20 mL of 0.25% bupivacaine for periarticular infiltration |
| Measure | Description | Time Frame |
|---|---|---|
| The amount of morphine consumption. | 24 hours postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Efficacy of pain control | Efficacy of pain control measured by
| 48 hours postoperative |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Thitima Chinachoti, M.D. | Contact | 66813082438 | sitci35@gmail.com | |
| Sathit Chairatthanawanit, M.D. | Contact | 66817902397 | sathit13@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Thitima Chinachoti, M.D. | Mahidol University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine Siriraj Hospital | Recruiting | Bangkok | 10700 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33238043 | Derived | Guay J, Kopp S. Peripheral nerve blocks for hip fractures in adults. Cochrane Database Syst Rev. 2020 Nov 25;11(11):CD001159. doi: 10.1002/14651858.CD001159.pub3. |
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| ID | Term |
|---|---|
| D005265 | Femoral Neck Fractures |
| ID | Term |
|---|---|
| D006620 | Hip Fractures |
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| D009020 | Morphine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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| D025981 |
| Hip Injuries |
| D007869 | Leg Injuries |
| D000588 |
| Amines |
| D009022 | Morphine Derivatives |
| D009019 | Morphinans |
| D053610 | Opiate Alkaloids |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D006572 | Heterocyclic Compounds, Bridged-Ring |
| D006576 | Heterocyclic Compounds, 4 or More Rings |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D010616 | Phenanthrenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D011083 | Polycyclic Compounds |