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This study is to compare and evaluate the effect of improving the carotid IMT and lipid level of the Cilostazol/Ginkgo leaf extract group with the aspirin administrated group in patients with diabetic peripheral angiopathy.
A Prospective, Randomized, Active-controlled, Parallel, Open, Multi-center, Phase IV
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Renexin CR 200/160mg | Experimental | Single oral administration of Renexin CR 200/160mg, QD |
|
| Aspirin 100mg | Active Comparator | Single oral administration of Aspirin 100mg, QD |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Renexin CR 200/160mg | Drug | Single oral administration of Renexin CR 200/160mg, QD |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in carotid IMT | Changes in carotid IMT after 24weeks, 48weeks of administration compared to before administration of investigational product | 24weeks, 48weeks |
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<Inclusion Criteria>
<Exclusion Criteria>
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| SKChemicals | Seongnam | Gyunggi-do | South Korea | |||
| SK chemicals |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40803668 | Derived | Hwang YC, Kim MK, Park JH, Yun HM, Kim SY, Lim S. Comparison of Efficacy and Safety of Cilostazol/Extract of Ginkgo biloba vs. Aspirin in Carotid Atherosclerosis in Patients with Diabetes Mellitus. Diabetes Metab J. 2026 Mar;50(2):357-367. doi: 10.4093/dmj.2025.0146. Epub 2025 Aug 13. |
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| Aspirin 100mg | Drug | Single oral administration of Aspirin 100mg, QD |
|
|
| Seoul |
| 110-744 |
| South Korea |
| ID | Term |
|---|---|
| D001241 | Aspirin |
| ID | Term |
|---|---|
| D012459 | Salicylates |
| D062385 | Hydroxybenzoates |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
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